摘要
该评论文章主要集中在有机整体材料上的对映分离技术。 本文概述了手性固定相及其在毛细管电色谱(CEC)和毛细管和纳米液相色谱(cLC和nLC)中的应用。自2000年以来,出版了数以千计的出版物,并引用所有这些文件将扩大审查的范围; 那么最近十年(2006年至2016年)的发展将会被提及。大多数情况下,将讨论基于由手性官能单体获得的共聚物的固定相和具有手性配体的有机整料的表面改性。 这些手性分离方法在几个分析领域的有效应用也将包括在内。
关键词: 有机整体材料,手性选择器,分子印迹聚合物,手性固定相,对映体分离,毛细管分离技术,毛细管电色谱,环糊精。
图形摘要
Current Medicinal Chemistry
Title:Application of Organic Monolithic Materials to Enantioseparation in Capillary Separation Techniques
Volume: 24 Issue: 8
关键词: 有机整体材料,手性选择器,分子印迹聚合物,手性固定相,对映体分离,毛细管分离技术,毛细管电色谱,环糊精。
摘要: This review article is primarily focused on the state-of-the-art of enantioseparations on organic monolithic materials. The article gives an overview of the chiral stationary phases and its application in capillary electrochromatography (CEC), and capillary- and nano-liquid chromatography (cLC and nLC). Since thousands of publications have been emerged from 2000’s and citing all these papers would extend the scope of this review; then, recent developments from last 10 years (2006 to 2016) will be mentioned. Mostly, stationary phases based on copolymers obtained from chiral functional monomers and surface modifications of organic monoliths with chiral ligands will be discussed. The effective application of these chiral separation methodologies in several analysis areas will be also included.
Export Options
About this article
Cite this article as:
Application of Organic Monolithic Materials to Enantioseparation in Capillary Separation Techniques, Current Medicinal Chemistry 2017; 24 (8) . https://dx.doi.org/10.2174/0929867324666170112100349
DOI https://dx.doi.org/10.2174/0929867324666170112100349 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Drug Delivery Systems for the Treatment of Diabetes Mellitus: State of the Art
Current Pharmaceutical Design Current Developments in Anti-Fungal Agents
Current Medicinal Chemistry - Anti-Infective Agents Topiramate in the New Generation of Drugs: Efficacy in the Treatment of Alcoholic Patients
Current Pharmaceutical Design Is Small Really Beautiful? Nanosensors and Low Abundance Biomarkers for Personalized Medicine
Current Pharmacogenomics and Personalized Medicine Bone Marrow Microenvironment: A Newly Recognized Target for Diabetes- Induced Cellular Damage
Endocrine, Metabolic & Immune Disorders - Drug Targets Update on Childhood Brucellosis
Recent Patents on Anti-Infective Drug Discovery Identifying the Cellular Targets of Bioactive Small Molecules with Activity-Based Probes
Current Medicinal Chemistry The Search for Molecular Determinants of LPS Inhibition by Proteins and Peptides
Current Topics in Medicinal Chemistry DNA Double Strand Breaks Repair Inhibitors: Relevance as Potential New Anticancer Therapeutics
Current Medicinal Chemistry Recent Patents on Oral Insulin Delivery
Recent Patents on Drug Delivery & Formulation New Inotropic Pharmacologic Strategies Targeting the Failing Myocardiumin the Newborn and Infant
Mini-Reviews in Medicinal Chemistry A Review of the Treatment of Psoriasis with Infliximab
Reviews on Recent Clinical Trials Integration of OMICS Technologies for Crop Improvement
Protein & Peptide Letters Recent Advances in Neuromyelitis Optica Spectrum Disorder: Pathogenesis, Mechanisms and Potential Treatments
Current Pharmaceutical Design Antibody Engineering for Targeted Therapy of Cancer Recombinant Fv-Immunotoxins
Current Pharmaceutical Biotechnology Indoxyl Sulfate: A Candidate Target for the Prevention and Treatment of Cardiovascular Disease in Chronic Kidney Disease
Current Drug Targets Prostaglandin D2 Receptors DP and CRTH2 in the Pathogenesis of Asthma
Current Molecular Medicine Hepatic Gene Transfer as a Means of Tolerance Induction to Transgene Products
Current Gene Therapy Multifunctional Dendritic Drug Delivery Systems: Design, Synthesis, Controlled and Triggered Release
Current Topics in Medicinal Chemistry Wound Healing Agents: The Role of Natural and Non-Natural Products in Drug Development
Mini-Reviews in Medicinal Chemistry