摘要
该评论文章主要集中在有机整体材料上的对映分离技术。 本文概述了手性固定相及其在毛细管电色谱(CEC)和毛细管和纳米液相色谱(cLC和nLC)中的应用。自2000年以来,出版了数以千计的出版物,并引用所有这些文件将扩大审查的范围; 那么最近十年(2006年至2016年)的发展将会被提及。大多数情况下,将讨论基于由手性官能单体获得的共聚物的固定相和具有手性配体的有机整料的表面改性。 这些手性分离方法在几个分析领域的有效应用也将包括在内。
关键词: 有机整体材料,手性选择器,分子印迹聚合物,手性固定相,对映体分离,毛细管分离技术,毛细管电色谱,环糊精。
图形摘要
Current Medicinal Chemistry
Title:Application of Organic Monolithic Materials to Enantioseparation in Capillary Separation Techniques
Volume: 24 Issue: 8
关键词: 有机整体材料,手性选择器,分子印迹聚合物,手性固定相,对映体分离,毛细管分离技术,毛细管电色谱,环糊精。
摘要: This review article is primarily focused on the state-of-the-art of enantioseparations on organic monolithic materials. The article gives an overview of the chiral stationary phases and its application in capillary electrochromatography (CEC), and capillary- and nano-liquid chromatography (cLC and nLC). Since thousands of publications have been emerged from 2000’s and citing all these papers would extend the scope of this review; then, recent developments from last 10 years (2006 to 2016) will be mentioned. Mostly, stationary phases based on copolymers obtained from chiral functional monomers and surface modifications of organic monoliths with chiral ligands will be discussed. The effective application of these chiral separation methodologies in several analysis areas will be also included.
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Cite this article as:
Application of Organic Monolithic Materials to Enantioseparation in Capillary Separation Techniques, Current Medicinal Chemistry 2017; 24 (8) . https://dx.doi.org/10.2174/0929867324666170112100349
DOI https://dx.doi.org/10.2174/0929867324666170112100349 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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