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Current Drug Safety

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ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

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Case Studies

Loss of Eyebrows and Eyelashes During Concomitant Treatment with Sitagliptin and Metformin

Author(s): Elena Succurro, Caterina Palleria, Mariafrancesca Ruffo, Raffaele Serra, Franco Arturi and Luca Gallelli

Volume 12, Issue 1, 2017

Page: [10 - 12] Pages: 3

DOI: 10.2174/1574886311666161014125536

Price: $65

Abstract

The fixed dose combination of sitagliptin 50 mg and metformin 850 mg (Janumet ®), is indicated for the treatment of type 2 diabetes mellitus in addition to diet and exercise to improve glycemic control in patients treated with metformin alone. Methods: We report a 69-year-old man with type 2 diabetes that developed sudden loss of eyebrows and eyelashes about 4 months after the beginning of Janumet®.

Clinical and laboratory findings excluded the presence of systemic or skin diseases able to induce these manifestations, while the Naranjo probability scale documented a possible association between the drug and the adverse drug reaction.

Keywords: Adverse drug reaction, metformin, sitagliptin, type 2 diabetes mellitus.

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