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Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Review Article

Investigations of Malignant Mesothelioma

Author(s): Jack A. Kastelik, Mahmoud Loubani, Gerard Avery, Anthony G. Arnold and Jaymin Morjaria

Volume 12, Issue 3, 2016

Page: [208 - 214] Pages: 7

DOI: 10.2174/1573398X12666160808151130

Price: $65

Abstract

Malignant mesothelioma is an aggressive form of cancer affecting the pleura and the serous membranes. Asbestos exposure has been shown to be the most important factor contributing to the development of malignant mesothelioma. The current guidelines suggest that investigations and management of patients with mesothelioma require multidisciplinary teamwork, which allows for imple-mentation of structured diagnostic algorithms resulting in more efficient and timely diagnosis and implementation of therapeutic strategies. Majority of patients with malignant mesothelioma present with pleural effusion. Therefore imaging including thoracic ultrasound, computed tomography and Positron Emission Tomography form an important part of investigations. However, in the context of malignant mesothelioma each of these imaging modalities has its limitations. For this reason, invasive procedures such as thoracocentesis, medical or surgical thoracoscopy remain important tools for obtaining histological diagnosis of malignant mesothelioma. In this review, we will discuss investigational approaches applied in diagnosing malignant mesothelioma.

Keywords: Investigations, malignant mesothelioma, radiology.

Graphical Abstract


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