摘要
在过去的十年中，一些放射性标记化合物已通过正电子发射断层扫描（PET）中的淀粉样蛋白体内成像。其中，氟比他班似乎是在大脑和其放射化学特性使其在临床常规使用的淀粉样斑块高亲和力的最可靠的一个。 本综述的目的是提供在18氟比他班体内应用概述，首先，描述的淀粉样蛋白的病理生理学基础。然后，这种放射性标记化合物的化学特性进行描述，特别注意合成过程和体内动力学。最后，将提供成像协议与图像解释综述以及将总结在先进和早期AD主题进行的主要研究的结果。
关键词: 淀粉样蛋白，阿尔茨海默病，氟比他班，正电子发射断层扫描，轻度认知障碍
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