摘要
背景:推进年龄与疼痛,睡眠问题和痴呆症患病率高。痴呆症经常伴随着令人痛心的行为和心理症状,包括睡眠问题。痴呆症睡眠问题的病因多因素。已经提出,未经治疗的疼痛可能有助于睡眠问题,并且已经显示疼痛治疗可以减少痴呆症患者的睡眠问题。 目的:本系统综述旨在概述调查痴呆症中疼痛和睡眠之间的关联和/或可能相互作用的研究。 方法:在MEDLINE,EMBASE,Cochrane和PsychINFO中进行系统检索,包括痴呆,疼痛和睡眠的文字和MESH术语。此外,检查了所附出版物中的参考列表以检索出版物。出版物必须调查与痴呆有关的睡眠和疼痛,以便纳入本次审查。 结果:搜索产生了1750次独立命中。在全文出版的49篇出版物中,共列出11篇出版物。只有一个对照试验被确定,并且代表了痛苦,睡眠和痴呆之间可能的相互作用关系的唯一见解。 6项包括的研究中疼痛或疼痛强度与睡眠有关,而其余研究既不能支持也不会与痴呆症患者的睡眠与疼痛之间的关系相抵触。没有一项研究采用客观的睡眠评估。 结论:需要高质量的研究调查痴呆症患者的睡眠和疼痛之间的相互作用,使用客观的睡眠测量和适合痴呆症患者的疼痛评估。
关键词: 阿尔茨海默病,痴呆症,养老院,疼痛,复查,睡眠。
Current Alzheimer Research
Title:Joint Occurrence of Pain and Sleep Disturbances in People with Dementia. A Systematic Review
Volume: 14 Issue: 5
关键词: 阿尔茨海默病,痴呆症,养老院,疼痛,复查,睡眠。
摘要: Background: Advancing age is associated with high prevalence of pain, sleep problems and dementia. Dementia is frequently accompanied by distressing behavioral and psychological symptoms, including sleep problems. The etiology of sleep problems in dementia is multifactorial. It has been suggested that untreated pain may contribute to sleep problems, and pain treatment has been shown to reduce sleep problems in people with dementia.
Objective: This systematic review aims to provide an overview of the studies that have investigated the association and/or possible interaction between pain and sleep in dementia. Methods: A systematic search was performed in MEDLINE, EMBASE, Cochrane and PsychINFO, including text words and MESH terms covering dementia, pain and sleep. Also, reference lists in the included publications were examined to retrieve publications. Publications had to investigate sleep and pain in relation to dementia to be included in this review. Results: The search produced 1750 independent hits. Out of the 49 publications studied in full text, 11 publications were included. Only one controlled trial was identified and represented the only insights to the possible interactional relationship between pain, sleep and dementia. Pain or pain intensity were related to sleep in 6 of the included studies, while the remaining studies could neither support nor contradict a relationship between sleep and pain in people with dementia. None of the studies employed objective sleep assessment. Conclusion: There is a need for high quality studies investigating the interaction between sleep and pain in people with dementia, using objective sleep measurements and pain assessment suitable for people with dementia.Export Options
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Cite this article as:
Joint Occurrence of Pain and Sleep Disturbances in People with Dementia. A Systematic Review, Current Alzheimer Research 2017; 14 (5) . https://dx.doi.org/10.2174/1567205013666160602234932
DOI https://dx.doi.org/10.2174/1567205013666160602234932 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
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