摘要
吩嗪是一类重要的杂环化合物,是药物化学领域的新兴化合物。它们具有多种生物活性,包括抗病毒、抗癌、抗老年痴呆、降糖、抗氧化、抗炎、抗菌等许多。本文重点综述化学性质和药物化学性质的应用,为未来应用吩恶嗪的治疗发展提供一个更深入的了解。
关键词: 吩嗪,放线菌素、吩嗪合成,吩嗪应用生物活性天然产物,吩嗪应用、吩嗪生物活性。
Current Medicinal Chemistry
Title:Advances of Phenoxazines: Synthesis, Reactivity and Their Medicinal Applications
Volume: 23 Issue: 26
Author(s): Sotirios Katsamakas, Alexandros L. Zografos, Vasiliki Sarli
Affiliation:
关键词: 吩嗪,放线菌素、吩嗪合成,吩嗪应用生物活性天然产物,吩嗪应用、吩嗪生物活性。
摘要: Phenoxazines are an important class of heterocycles, which are emerging in the field of medicinal chemistry. They exhibit numerous biological activities, including antiviral, anticancer, anti-Alzheimer, antidiabetic, antioxidant, anti-inflammatory, antibiotic and many more. The present review focuses on the chemistry along with the medicinal applications of the phenoxazine moiety, in order to provide a greater insight for the development of future phenoxazine therapeutics.
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Cite this article as:
Sotirios Katsamakas, Alexandros L. Zografos, Vasiliki Sarli , Advances of Phenoxazines: Synthesis, Reactivity and Their Medicinal Applications, Current Medicinal Chemistry 2016; 23 (26) . https://dx.doi.org/10.2174/0929867323666160510123023
DOI https://dx.doi.org/10.2174/0929867323666160510123023 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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