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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

Recent Advances in the Synthesis of 1,3-Azoles

Author(s): Nadale K. Downer-Riley and Yvette A. Jackson

Volume 16, Issue 30, 2016

Page: [3617 - 3626] Pages: 10

DOI: 10.2174/1568026616666160414122349

Price: $65

Abstract

The 1,3-azole motif is a common and integral feature of many clinical drugs. Due to their wide-ranging applications, the development of 1,3-azoles as therapeutic agents is an ongoing focus of medicinal chemists. This review highlights the recent approaches towards the assembly of 1,3-oxazole, 1,3-thiazole and 1,3-imidazole motifs.

Keywords: 1, 3-Azoles, Imidazole, Oxazole, Synthesis, Therapeutic agent, Thiazole.

Graphical Abstract


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