Abstract
Chemotherapy is the major and most widely used therapeutic strategy for the treatment of a wide variety of cancers. The non-specific/non-targeted drug delivery in chemotherapy leads to undesired side effects in normal and healthy tissues, and insufficient dosages to kill cancerous cells. Now-a-days, smart and intelligent multifunctional targeted nanomedicines based on various nanocarriers (dendrimers, carbon nanotubes, graphene, nanoparticles, quantum dots, self-emuslifying lipidic systems and carbon nanohorns etc) are being investigated promisingly in cancer treatment. In this article, we review the role of smart and intellegent multifucntional nanocarriers in delivery of chemotherapeutic agents with the aim to develop promising treatment strategy to combat with one of the killer of man kind i.e. cancer.
Keywords: Chemotherapy, multifunctional, dendrimers, carbon nanotubes, drug delivery, drug targeting.
Current Pharmaceutical Design
Title:Design of multifunctional nanocarriers for delivery of anti-cancer therapy
Volume: 21 Issue: 42
Author(s): Neelesh Kumar Mehra, Keerti Jain and Narendra Kumar Jain
Affiliation:
Keywords: Chemotherapy, multifunctional, dendrimers, carbon nanotubes, drug delivery, drug targeting.
Abstract: Chemotherapy is the major and most widely used therapeutic strategy for the treatment of a wide variety of cancers. The non-specific/non-targeted drug delivery in chemotherapy leads to undesired side effects in normal and healthy tissues, and insufficient dosages to kill cancerous cells. Now-a-days, smart and intelligent multifunctional targeted nanomedicines based on various nanocarriers (dendrimers, carbon nanotubes, graphene, nanoparticles, quantum dots, self-emuslifying lipidic systems and carbon nanohorns etc) are being investigated promisingly in cancer treatment. In this article, we review the role of smart and intellegent multifucntional nanocarriers in delivery of chemotherapeutic agents with the aim to develop promising treatment strategy to combat with one of the killer of man kind i.e. cancer.
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Cite this article as:
Mehra Kumar Neelesh, Jain Keerti and Jain Kumar Narendra, Design of multifunctional nanocarriers for delivery of anti-cancer therapy , Current Pharmaceutical Design 2015; 21 (42) . https://dx.doi.org/10.2174/1381612821666151027153106
DOI https://dx.doi.org/10.2174/1381612821666151027153106 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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