Novel and Emerging Targeted Therapies of Colorectal Cancer

Title:Novel and Emerging Targeted Therapies of Colorectal Cancer

Volume: 10 Issue: 4

Author(s): Niklas Finnberg, Prashanth Gokare and Wafik S. El-Deiry

Affiliation:

Keywords: Clinical, colorectal cancer, DPYD, RAS, targeted therapy, TRAIL.

Abstract: The survival rate of patients with colorectal cancer (CRC) is steadily increasing over the past decade. However, CRC continue to be one of the leading causes of cancer-related fatality in the United States. Current targeted strategies offer limited clinical benefits and the overall survival rate for CRC remains low. Improved understanding of the molecular changes associated with CRC that control growth factor signaling and evasion of cell death allow for the development of improved targeted therapy. This review aims to discuss some of the emerging therapies aimed to target CRC.

Cite this article as:

Finnberg Niklas, Gokare Prashanth and El-Deiry S. Wafik, Novel and Emerging Targeted Therapies of Colorectal Cancer, Current Clinical Pharmacology 2015; 10 (4) . https://dx.doi.org/10.2174/1574884710666151020095911