Abstract
In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.
Graphical Abstract
Anti-Cancer Agents in Medicinal Chemistry
Title: Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold
Volume: 16 Issue: 5
Author(s): Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong-Shin Chang, Kyeong Lee and Yongseok Choi
Affiliation:
Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.
Abstract: In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
Export Options
About this article
Cite this article as:
Singh Sarbjit, Goo Jail, Gajulapati Veeraswamy, Chang Tong-Shin, Lee Kyeong and Choi Yongseok, Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold , Anti-Cancer Agents in Medicinal Chemistry 2016; 16 (5) . https://dx.doi.org/10.2174/1871520615666150916091750
DOI https://dx.doi.org/10.2174/1871520615666150916091750 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Meet Our Editorial Board Member
Anti-Cancer Agents in Medicinal Chemistry Synthesis and in vitro Anti-tumor Activity of Some New Sebacoyl Chloride Based Heterocycles
Current Organic Synthesis Extracellular ATP and Neurodegeneration
Current Drug Targets - CNS & Neurological Disorders Application of Outer Membrane Vesicle of Neisseria meningitidis Serogroup B as a New Adjuvant to Induce Strongly Th1-Oriented Responses Against HIV-1
Current HIV Research Multidrug Resistance Through the Spectacle of P-Glycoprotein
Current Cancer Drug Targets Synthesis of Biologically Active Selenium-Containing Molecules From Greener Perspectives
Current Green Chemistry Meet Our Section Editor
Current Cancer Drug Targets Cell-Selective Mitochondrial Targeting: Progress in Mitochondrial Medicine
Current Drug Delivery Skp2 Inhibitors: Novel Anticancer Strategies
Current Medicinal Chemistry Antibody Functional Assays as Measures of Fc Receptor-Mediated Immunity to HIV - New Technologies and their Impact on the HIV Vaccine Field
Current HIV Research SUMOylation Modulates CFTR Biogenesis: Is the Pathway Druggable?
Current Drug Targets State of the Art Clinical Efficacy and Safety Evaluation of N-Acetylcarnosine Dipeptide Ophthalmic Prodrug. Principles for the Delivery, Self-Bioactivation, Molecular Targets and Interaction with a Highly Evolved Histidyl-Hydrazide Structure in the Treatment and Therapeutic Management of a Group of Sight-Threatening Eye Diseases
Current Clinical Pharmacology Contrast Enhanced Ultrasonography for Focal Liver Lesions Characterization: Clinical Perspective
Current Medical Imaging Novel VEGF-independent Strategies Targeting Tumor Vasculature: Clinical Aspects
Current Pharmaceutical Design Control of Melanoma Invasiveness by Anticollagenolytic Agents: A Reappraisal of an Old Concept
Anti-Cancer Agents in Medicinal Chemistry Managing Skin Malignancies- How Family Doctors, Plastic Surgeons, and Dermatologists Can Help
Current Cancer Therapy Reviews Aneuploidy-Inducing Mutations in Mitotic Checkpoint Protein hMad1-Carboxi Terminal Domain Analyzed by SAR and Computational Mutagenesis
Current Proteomics Protein Kinase C and Prostate Carcinogenesis: Targeting the Cell Cycle and Apoptotic Mechanisms
Current Drug Targets Formulated Squalene for Food Related Applications
Recent Patents on Food, Nutrition & Agriculture Dendritic Cell-Based Immune Therapy in Liver Diseases
Current Immunology Reviews (Discontinued)