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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride

Author(s): Amin Zolali, Farough Nasiri and Sonia Omid-Niakan

Volume 17, Issue 7, 2014

Page: [610 - 613] Pages: 4

DOI: 10.2174/1386207317666140313110334

Price: $65

Abstract

An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without the need to use any catalyst.

Keywords: 1, 3-Thiazine, dithiocarbamate, MCRs, multicomponent, one-pot.


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