Synthesis of Alkaloid Natural Products Using Solid-Supported Reagents and Scavengers

Title: Synthesis of Alkaloid Natural Products Using Solid-Supported Reagents and Scavengers

Volume: 9 Issue: 15

Author(s): I. R. Baxendale and S. V. Ley

Affiliation:

Keywords: organic synthesis, purification techniques, reagent immobilization, amaryllidaceae alkaloids, nornicotine, polymer-supported carbonate, trifluoroacetamide

Abstract: Supported reagents and scavengers have become key tools for the synthesis of biologically important molecular entities. The complexity of the target molecules attainable and the synthetic flexibility afforded by these systems now rivals any solution phase approach whilst offering the added advantage of rapid purification and work-up. This short review highlights the application of these immobilized reagents to the preparation of alkaloid natural products.

Cite this article as:

Baxendale R. I. and Ley V. S., Synthesis of Alkaloid Natural Products Using Solid-Supported Reagents and Scavengers, Current Organic Chemistry 2005; 9 (15) . https://dx.doi.org/10.2174/138527205774370513