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Current Drug Targets

Editor-in-Chief

ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

Plasminogen Activator Inhibitor-1 and Restenosis

Author(s): Nadish Garg and William P. Fay

Volume 8, Issue 9, 2007

Page: [1003 - 1006] Pages: 4

DOI: 10.2174/138945007781662355

Price: $65

Abstract

Despite the introduction of drug-eluting stents restenosis remains an important clinical problem. In this review we examine the role of plasminogen activator inhibitor-1 (PAI-1) in controlling restenosis after balloon angioplasty and stent implantation.

Keywords: Urokinase, vascular wall, restenosis, carotid artery ligation, VSMC proliferation

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