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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Involvement of MAPK Signalling in Human Villous Trophoblast Differentiation

Author(s): C. Vaillancourt, D. Lanoix, F. Le Bellego, G. Daoud and J. Lafond

Volume 9, Issue 8, 2009

Page: [962 - 973] Pages: 12

DOI: 10.2174/138955709788681663

Price: $65

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Abstract

Human villous trophoblast differentiation is a complex and highly regulated process essential for the well-being of the pregnancy and fetal development. In this review, we present an overview of the role of MAPKs signalling in morphological and functional differentiation of villous trophoblast.

Keywords: Human placenta, villous cytotrophoblast, differentiation, mitogen-activated protein kinases, cell signalling, syncytiotrophoblast, peroxisome proliferator-activated receptors, Src family kinase, drug


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