The Role of Aβ Peptides in Alzheimers Disease

Title: The Role of Aβ Peptides in Alzheimers Disease

Volume: 12 Issue: 6

Author(s): Anna K. Tickler, John D. Wade and Frances Separovic

Affiliation:

Keywords: amyloid, peptide, alzheimers disease, structure, therapeutic

Abstract: The Aβ peptide has been identified as central to the onset and development of Alzheimers disease (AD) and several hypotheses about toxicity involving Aβ peptides have been proposed including mechanisms of oxidative stress and disruption of calcium homeostasis. The biology, structure and physical properties of Aβ peptides are discussed, as well as existing therapeutics and future strategies for the treatment of AD.

Cite this article as:

Tickler K. Anna, Wade D. John and Separovic Frances, The Role of Aβ Peptides in Alzheimers Disease, Protein & Peptide Letters 2005; 12 (6) . https://dx.doi.org/10.2174/0929866054395905