Abstract
Chiral derivative 3 has been recognized as a precursor of enantiopure 2,3-disubstituted piperidines. A study concerning the chemoselective reduction, using BH3.Me2S, of highly functionalised compounds 6 and N-BOC aminoacid 12 is reported.
Keywords: Asymmetric synthesis, pipecolic acids, piperidines, phenylglycinol, aza-annelation
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