Abstract
The number of synthetic applications of epoxide hydrolases in organic chemistry has reached a remarkable level. This has been due to a tremendous amount of work dedicated to the discovery of novel epoxide hydrolases from various biological sources, understanding the structure and function of these widespread enzymes and last but not least, the stabilization of these biocatalysts by various means for production purposes.
Keywords: Oxiranes, Enantioselectivity, Enantioconvergence, Kinetic Resolution, Desymmetrization, Asymmetric Synthesis, Biotransformation, Biocatalysis, Vicinal Diol, Chiral Synthon, Building Block, Epoxide hydrolases (EHs), chlorohydrins, epoxides, Aspergillus niger Gbcf 79
Current Organic Chemistry
Title: Epoxide Hydrolases and their Application in Organic Synthesis
Volume: 16 Issue: 4
Author(s): Michael Kotik, Alain Archelas and Roland Wohlgemuth
Affiliation:
Keywords: Oxiranes, Enantioselectivity, Enantioconvergence, Kinetic Resolution, Desymmetrization, Asymmetric Synthesis, Biotransformation, Biocatalysis, Vicinal Diol, Chiral Synthon, Building Block, Epoxide hydrolases (EHs), chlorohydrins, epoxides, Aspergillus niger Gbcf 79
Abstract: The number of synthetic applications of epoxide hydrolases in organic chemistry has reached a remarkable level. This has been due to a tremendous amount of work dedicated to the discovery of novel epoxide hydrolases from various biological sources, understanding the structure and function of these widespread enzymes and last but not least, the stabilization of these biocatalysts by various means for production purposes.
Export Options
About this article
Cite this article as:
Kotik Michael, Archelas Alain and Wohlgemuth Roland, Epoxide Hydrolases and their Application in Organic Synthesis, Current Organic Chemistry 2012; 16 (4) . https://dx.doi.org/10.2174/138527212799499840
DOI https://dx.doi.org/10.2174/138527212799499840 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Editorial (Hot Topic: Vitamin D Deficiency and Critical Illness)
Inflammation & Allergy - Drug Targets (Discontinued) Coffee and Depression: A Short Review of Literature
Current Pharmaceutical Design Structure-based Drug Design Targeting Biosynthesis of Isoprenoids: A Crystallographic State of the Art of the Involved Enzymes
Current Protein & Peptide Science Ketamine as Antidepressant? Current State and Future Perspectives
Current Neuropharmacology Inflammasome as a New Therapeutic Target for Diabetic Complications
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases
Current Medicinal Chemistry Hypocholesterolemia
Current Vascular Pharmacology Docking Studies for Multi-Target Drugs
Current Drug Targets Role of Open Source Tools and Resources in Virtual Screening for Drug Discovery
Combinatorial Chemistry & High Throughput Screening Biologic Therapies in Primary Sjögren's Syndrome
Current Pharmaceutical Biotechnology Vitamin D Deficiency May Be Associated with a More Rapid Decline in CD4 Cell Count to <350 Cells/µL in Untreated HIV-Infected Adults
Current HIV Research Microbial Biotransformation: Recent Developments on Steroid Drugs
Recent Patents on Biotechnology The Long Pentraxin PTX3, a Soluble Pattern Recognition Receptor Involved in Innate Immunity,Inflammation and Female Fertility
Current Immunology Reviews (Discontinued) The Need for Diagnostic Criteria in Systemic Vasculitis
Current Immunology Reviews (Discontinued) A Review on the Phytochemicals, Ethnomedicine Uses and Pharmacology of Ficus Species
Current Traditional Medicine Prediction of MicroRNA–disease Associations by Matrix Completion
Current Proteomics Genetic Insights into Sepsis: What have we Learned and How will it Help?
Current Pharmaceutical Design Biomarkers Associated with Vulnerable Atheromatous Plaque
Current Medicinal Chemistry Dendritic Cells in Pathogenesis of COPD
Current Pharmaceutical Design The Relationship Between HIV Infection and Cardiovascular Disease
Current Cardiology Reviews