Abstract
Metabolic syndrome (MetS) is a cluster of risk factors, each one individually associated with increased cardiovascular disease risk. Treatment of all components of MetS is expected to result in reduced risk. Treatment of MetS mainly includes lifestyle changes. In addition, drug therapy may be considered, especially combinations of different drugs, in order to tackle all the features of MetS. We review the therapeutic strategies currently used for obesity and dyslipidemia treatment in patients with MetS, with a focus on drug combinations.
Keywords: Bile acid sequestrants, ezetimibe, fibrates, metabolic syndrome, niacin, orlistat, rimonabant, statins
Current Pharmaceutical Design
Title: Drug Combinations for Dyslipidemia and Obesity Treatment in Metabolic Syndrome
Volume: 15 Issue: 29
Author(s): M. Florentin, M. S. Elisaf, D. P. Mikhailidis and E. N. Liberopoulos
Affiliation:
Keywords: Bile acid sequestrants, ezetimibe, fibrates, metabolic syndrome, niacin, orlistat, rimonabant, statins
Abstract: Metabolic syndrome (MetS) is a cluster of risk factors, each one individually associated with increased cardiovascular disease risk. Treatment of all components of MetS is expected to result in reduced risk. Treatment of MetS mainly includes lifestyle changes. In addition, drug therapy may be considered, especially combinations of different drugs, in order to tackle all the features of MetS. We review the therapeutic strategies currently used for obesity and dyslipidemia treatment in patients with MetS, with a focus on drug combinations.
Export Options
About this article
Cite this article as:
Florentin M., Elisaf S. M., Mikhailidis P. D. and Liberopoulos N. E., Drug Combinations for Dyslipidemia and Obesity Treatment in Metabolic Syndrome, Current Pharmaceutical Design 2009; 15 (29) . https://dx.doi.org/10.2174/138161209789105054
DOI https://dx.doi.org/10.2174/138161209789105054 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Rational Discovery of Novel Squalene Synthase Inhibitors through Pharmacophore Modelling
Current Computer-Aided Drug Design Ryanodine Receptor Patents
Recent Patents on Biotechnology Antioxidant Activity of Resveratrol Analogs
Letters in Drug Design & Discovery Effects of Immunosenescence on the Lower Expression of Surface Molecules in Neutrophils and Lymphocytes
Current Aging Science Pattern of Medication Use Among Older Inpatients in Seven Hospitals in Italy: Results from the Criteria to Assess Appropriate Medication Use Among Elderly Complex Patients (CRIME) Project
Current Drug Safety Folate and Homocysteine Metabolism: Therapeutic Targets in Cardiovascular and Neurodegenerative Disorders
Current Medicinal Chemistry Pesticides-induced Cardiovascular Dysfunctions: Prevalence and Associated Mechanisms
Current Hypertension Reviews Inflammation in Fish As Seen from A Morphological Point of View with Special Reference to the Vascular Compartment
Current Pharmaceutical Design The Potential of Statins for Individualized Colorectal Cancer Chemoprevention
Current Drug Targets MicroRNA-21 as Therapeutic Target in Cancer and Cardiovascular Disease
Recent Patents on Cardiovascular Drug Discovery Dietary Compounds, Epigenetic Modifications and Metabolic Diseases
Current Chemical Biology Oxidative Stress During Myocardial Ischaemia and Heart Failure
Current Pharmaceutical Design The Role of Mineralocorticoid Receptor Antagonists in the Management of Heart Failure with Preserved Ejection Fraction
Current Pharmaceutical Design Editorial [Hot Topic: Natural Products for the Healthy Heart (Guest Editor : Dipak K. Das)]
Current Pharmaceutical Biotechnology The Therapeutic Potential of Rutin for Diabetes: An Update
Mini-Reviews in Medicinal Chemistry Antithrombotic Therapy
Current Molecular Medicine Therapeutic Applications of Calcium Metabolism Modulation in Heart Disease
Medicinal Chemistry Chemoprevention of Lung Pathologies by Dietary n-3 Polyunsaturated Fatty Acids
Current Medicinal Chemistry Endotoxin, Toll-like Receptor-4, and Atherosclerotic Heart Disease
Current Cardiology Reviews Hypertension and Cardiac Arrhythmias
Current Pharmaceutical Design