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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

Pharmacological Chemistry and Biomedical Implications of Chemical Ingredients from Parthenium hysterophorus

Author(s): Jyotsna Jaiswal, Nitika Singh, Vivek Kumar Gupta, Pawan Kumar Doharey, Nikhat Jamal Siddiqi and Bechan Sharma*

Volume 22, Issue 23, 2022

Published on: 30 March, 2022

Page: [1950 - 1965] Pages: 16

DOI: 10.2174/1568026622666220307145027

Price: $65

Abstract

Parthenium hysterophorus L. belonging to the family Asteraceae is a noxious weed infestation with allelopathic effects with its lower economic value. It poses a serious risk to its surroundings. The presence of oils, polyphenols, flavones, flavonoids, alkaloids, terpenes, pseudoguaianolides, and histamines in P. hysterophorus makes it important and beneficial due to its medicinal properties. This review article is focused on the history, geographical distribution, chemical composition, and molecular structure of some phytochemicals and ethanopharmacological aspects of P. hysterophorus. The harmful effects of this weed have also been included. The information available from the existing literature revealed that P. hysterophorus is rich in various phytochemicals with different pharmacological activities. However, the complete analysis of different phytoconstituents isolated from P. hysterophorus and their specific properties are not fully understood. The sporadic information published in some journals suggests that this plant could be exploited to develop new drugs against certain diseases, including cancer, HIV-1 infection, and immunological disorders. The structure and mode of action of some compounds such as parthenin and stigmasterol were also discussed. Though the current information on P. hysterophorus indicates the ethnopharmacological implications of extracts of this plant, more systematic and extensive studies are still required to properly understand the contribution of its specific chemical constituents responsible for their various medicinal properties.

Keywords: Parthenium hysterophorus, Ethanopharmacological aspects, Parthenin, Phytochemistry, Allelopathic, Phytochem-icals.

Graphical Abstract

[1]
Legesse, A.; Tesfaye, G.; Tegene, G. Exploring of the potential of parthenium weed ash as substitute for commercial alkali for preparation of laundry soap: As a means to control invasion of Parthenium. Front. Sustain, 2021, 2, 1-12.
[2]
Adkins, S.; Shabbir, A. Biology, ecology and management of the invasive parthenium weed (Parthenium Hysterophorus L.). Pest Manag. Sci., 2014, 70(7), 1023-1029.
[http://dx.doi.org/10.1002/ps.3708]
[3]
Mekonnen, G. Threats and management options of Parthenium (Parthenium Hysterophorus L.) in Ethiopia. Agric. Res. Technol. Open Access J, 2017, 10, 1-7.
[4]
Patel, S. Harmful and beneficial aspects of Parthenium Hysterophorus: An update. Biotech, 2011, 1, 1-9.
[5]
Mtenga, N.C.; Tarimo, T.M.; Ndakidemi, P.A.; Mbega, E.R. Carrot-weed: A noxious plant that threatens biodiversity in Africa. Am. J. Plant Sci., 2019, 10(3), 433-446.
[http://dx.doi.org/10.4236/ajps.2019.103031]
[6]
Ahmad, J.; Bagheri, R.; Bashir, H.; Baig, M.A.; Al-Huqail, A.; Ibrahim, M.M.; Qureshi, M.I. Organ-specific phytochemical profiling and antioxidant analysis of Parthenium Hysterophorus L. BioMed Res. Int., 2018, 2018, 1-10.
[http://dx.doi.org/10.1155/2018/9535232]
[7]
Kaur, M.; Aggarwal, N.K.; Kumar, V.; Dhiman, R. Effects and management of Parthenium Hysterophorus: A weed of global significance. Int. Sch. Res. Notices, 2014, 2014, 1-14.
[http://dx.doi.org/10.1155/2014/368647]
[8]
Bhateria, R. Renu; Snehlata, Parthenium Hysterophorus L.: Harmful and beneficial aspects - a review. Nat. Environ. Pollut. Technol., 2015, 14, 463-474.
[9]
Paudel, V.R. Parthenium Hysterophorus L., a noxious invasive weed. Bot. Orient., 2009, 6, 85-92.
[http://dx.doi.org/10.3126/botor.v6i0.2915]
[10]
Motmainna, M.; Juraimi, A.S.; Uddin, M.K.; Asib, N.B.; Islam, A.K.M.M.; Ahmad Hamdani, M.S.; Hasan, M. Phytochemical constituents and allelopathic potential of Parthenium Hysterophorus L. in comparison to commercial herbicides to control weeds. Plants, 2021, 10(7), 1445.
[http://dx.doi.org/10.3390/plants10071445]
[11]
Saini, A.; Aggarwal, N.K.; Sharma, A.; Kaur, M.; Yadav, A. Utility potential of Parthenium Hysterophorus for its strategic management. Adv. Agric., 2014, 2014, 1-16.
[12]
Fernandez-Quintanilla, C.; Quadranti, M.; Kudsk, P.; Bàrberi, P. Which future for weed science? Weed Res., 2008, 48(4), 297-301.
[http://dx.doi.org/10.1111/j.1365-3180.2008.00642.x]
[13]
Kaur, L.; Malhi, D.S.; Cooper, R.; Kaur, M.; Sohal, H.S.; Mutreja, V.; Sharma, A. Comprehensive review on ethnobotanical uses, phytochemistry, biological potential and toxicology of Parthenium Hysterophorus L.: A journey from noxious weed to a therapeutic medicinal plant. J. Ethnopharmacol., 2021, 281, 114525.
[http://dx.doi.org/10.1016/j.jep.2021.114525]
[14]
Agarwal, K.; D’Souza, M. Airborne contact dermatitis induced by parthenium: A study of 50 cases in South India. Nat. Environ. Pollut. Technol, 2008, 34, 4-6.
[15]
Bajwa, A.A.; Weston, P.A.; Gurusinghe, S.; Latif, S.; Adkins, S.W.; Weston, L.A. Toxic Potential and metabolic profiling of two Australian biotypes of the invasive plant parthenium weed (Parthenium Hysterophorus L.). Toxins (Basel), 2020, 12(7), 447.
[http://dx.doi.org/10.3390/toxins12070447]
[16]
Kreuger, M.R.O.; Grootjans, S.; Biavatti, M.W.; Vandenabeele, P.; D’Herde, K. Sesquiterpene lactones as drugs with multiple targets in cancer treatment: Focus on parthenolide. Anticancer Drugs, 2012, 23(9), 883-896.
[http://dx.doi.org/10.1097/CAD.0b013e328356cad9]
[17]
Maishi, A.I.; Shoukat Ali, P.K.; Chaghtai, S.A.; Khan, G. A proving of Parthenium Hysterophorus, L. Br. Homeopath. J., 1998, 87(1), 17-21.
[http://dx.doi.org/10.1016/S0007-0785(98)80005-7]
[18]
Singh, H.P.; Batish, D.R.; Kohli, R.K.; Saxena, D.B.; Arora, V. Effect of parthenin - a sesquiterpene lactone from Parthenium Hysterophorus - On early growth and physiology of Ageratum conyzoides. J. Chem. Ecol., 2002, 28(11), 2169-2179.
[http://dx.doi.org/10.1023/A:1021089013754]
[19]
Jayaramiyah, R.; Ramesh, B.N.; Krishnaprasad, B.T.; Sunil Kumar, R.; Pramodh, G.; Rajkumar, C.; Sheshadri, T. Harmful effects of Parthenium Hysterophorus and management through different approaches- a review. Ann. Plant Sci., 2017, 6, 1614.
[http://dx.doi.org/10.21746/aps.2017.05.002]
[20]
Shi, B.; Dhileepan, K.; Adkins, S. The impact of parthenium weed-amended substrates on the germination and early growth of a range of pasture and crop species. Agronomy (Basel), 2021, 11(9), 1708.
[http://dx.doi.org/10.3390/agronomy11091708]
[21]
Dukpa, R.; Tiwari, A.; Kapoor, D. Biological management of allelopathic plant Parthenium sp. Open Agric., 2020, 1(1), 252-261.
[http://dx.doi.org/10.1515/opag-2020-0027]
[22]
Kumar, S.; Singh, A.P.; Nair, G.; Batra, S.; Seth, A.; Wahab, N.; Warikoo, R. Impact of Parthenium Hysterophorus leaf extracts on the fecundity, fertility and behavioural response of Aedes Aegypti L. Parasitol. Res., 2011, 108(4), 853-859.
[http://dx.doi.org/10.1007/s00436-010-2126-1]
[23]
Belz, R.G.; Reinhardt, C.F.; Foxcroft, L.C.; Karl, H. Residual allelopathy in Parthenium Hysterophorus L. Does parthenin play a leading role? Crop Prot., 2007, 26(3), 237-245.
[http://dx.doi.org/10.1016/j.cropro.2005.06.009]
[24]
Netsere, A.; Mendesil, E. Allelopathic effects of Parthenium Hysterophorus L. aqueous extracts on soybean (Glycine max L.) and haricot bean (Phaseolus vulgaris L.) seed). seed germination, shoot and root growth and dry matter production. J. Appl. Bot. Food Qual., 2011, 84, 219-222.
[25]
Gnanavel, I. Parthenium Hysterophorus L.: A major threat to natural and agro eco-systems in India. Sci. Int. (Lahore), 2013, 1(5), 124-131.
[http://dx.doi.org/10.5567/sciintl.2013.124.131]
[26]
Lakshmi, C.; Srinivas, C. Parthenium the terminator: An update. Indian Dermatol. Online J., 2012, 3(2), 89-100.
[http://dx.doi.org/10.4103/2229-5178.96698]
[27]
Singh, R.K.; Kumar, S.; Kumar, S.; Kumar, A. Development of parthenium based activated carbon and its utilization for adsorptive removal of P-Cresol from aqueous solution. J. Hazard. Mater., 2008, 155(3), 523-535.
[http://dx.doi.org/10.1016/j.jhazmat.2007.11.117]
[28]
Parashar, V.; Parashar, R.; Sharma, B.; Pandey, A.C. Parthenium leaf extract mediated synthesis of nanoparticles: A novel approach towards weed utilization. Digest. J. Nanomaters. BIOS, 2009, 4, 45-50.
[29]
Sandilyan, S. Strategies for control and management of some selective Invasive Alien Plant Species Endangering Indian Biodiversity; NBA Chennai, 2019, pp. 4-72.
[30]
Gupta, N.; Martin, B.M.; Metcalfe, D.D.; Rao, P.V.S. Identification of a novel hydroxyproline-rich glycoprotein as the major allergen in parthenium pollen. J. Allergy Clin. Immunol., 1996, 98(5), 903-912.
[http://dx.doi.org/10.1016/S0091-6749(96)80006-6]
[31]
Girish, S.; Harshini, M.; Ravi, L. A review on pharmaceutical potential of parthenium plant. Asian J. Pharm., 2020, 14, 156.
[32]
Taye, T.; Gossmann, M.; Einhorn, G.; Büttner, C.; Metz, R.; Abate, D. The potential of pathogens as biological control of parthenium weed(Parthenium hystrophorus L.) in Ethopia. Meded Rijksuniv Gent Fak Landbouwkd Toegep Biol Wet., 2002, 67, 409-420.
[33]
Kanaujia, G.; Meena, R.K.; Verma, V.K.; Tiwari, A.; Shukla, S.; Verma, S.; Singh, R. Impact and management of Parthenium hysterophorus. G.J.B, 2018, 6, 15-18.
[34]
Ishizuka, K.; Tsutsumi, Y.; Baba, M.; Biyani, R.; Meng, C.W.; Biyani, M.; Takagi, M.; Jaiswal, J.; Sharma, B.; Kojima, K.; Takita, T.; Yasukawa, K. Inhibition of HIV-1 reverse transcriptase activity by the extracts of Indian plants. J. Biol. Macromol., 2020, 20(1), 17-22.
[http://dx.doi.org/10.14533/jbm.20.17]
[35]
Das, B.; Venkataiah, B.; Kashinathan, A. (+) Syringaresinol from Parthenium Hysterophorus. Fitoterapia, 1999, 70(1), 101-102.
[http://dx.doi.org/10.1016/S0367-326X(98)00014-8]
[36]
Kumar, S.; Pandey, A.K. Chemistry and biological activities of flavonoids: An overview. ScientificWorldJ., 2013, 2013, 1-16.
[http://dx.doi.org/10.1155/2013/162750]
[37]
Gurib-Fakim, A. Medicinal plants: Traditions of yesterday and drugs of tomorrow. Mol. Aspects Med., 2006, 27(1), 1-93.
[http://dx.doi.org/10.1016/j.mam.2005.07.008]
[38]
Bezuneh, T.T. Phytochemistry and antimicrobial activity of Parthenium Hysterophorus L.: A review. Sci. J. Anal. Chem., 2015, 3(3), 30.
[http://dx.doi.org/10.11648/j.sjac.20150303.11]
[39]
Joshi, A.; Bachheti, R.K.; Sharma, A.; Mamgain, R. Parthenium Hysterophorus. L. (Asteraceae) : A boon or curse? (A review). Orient. J. Chem., 2016, 32(3), 1283-1294.
[http://dx.doi.org/10.13005/ojc/320302]
[40]
Parthasarathi, T.; Suganya, V.; Sivakumar, R. Allelopathic effect of aqueous leaf extract of Parthenium Hysterophorus L. on seed germination and seedling growth in greengram, blackgram and groundnut. Madras Agric. J., 2017, 99, 514-517.
[41]
Roth, I.; Blievernicht, A.; Buttner, C.; Tewodros, T.; Goswami, A.; Mewis, I.; Ulrichs, C. Insecticidal effects of Parthenium Hysterophorus extracts rich in terpenoids and phenolic acids. J. Plant Dis. Prot., 2008, 115, 43-43.
[42]
Zhou, J. Encyclopedia of traditional Chinese Medicines molecular structures, pharmacological activities, natural sources and applications.Isolated Compounds H-M; Springer, 2011, p. 3.
[43]
Kuhn, M.A.; Winston, D. Herbal therapy and supplements: A scientific and traditional approach; Lippincott Williams & Wilkins 2000.
[44]
Barnes, J.; Anderson, L.A.; Phillipson, J.D. Herbal Medicines; Pharmaceutical Press: London, UK, 2007.
[45]
Roy, D.C.; Shaik, M.M. Toxicology, phytochemistry, bioactive compounds and pharmacology of Parthenium Hysterophorus. J. Med. Plants Stud., 2013, 1, 126-141.
[46]
Begum, G.; Dastagir, G.; Rauf, A.; Bawazeer, S.; Rahman, K.U.; Ramadan, M.F. Pharmacognostic characteristics and phytochemical profile of various parts of Parthenium Hysterophorus. Rend. Lincei Sci. Fis. Nat., 2020, 31(3), 853-872.
[http://dx.doi.org/10.1007/s12210-020-00911-z]
[47]
Venkataiah, B.; Ramesh, C.; Ravindranath, N.; Das, B. Charminarone, a seco-pseudoguaianolide from Parthenium Hysterophorus. Phytochemistry, 2003, 63(4), 383-386.
[http://dx.doi.org/10.1016/S0031-9422(03)00147-X]
[48]
Zhou, J.; Xie, G.; Yan, X. Encyclopedia of traditional chinese medicines-molecular structures, pharmacological activities, natural sources and applications.Isolated Compounds TZ; Springer Berlin Heidelberg, 2011.
[49]
Boon, H.; Smith, M. The Complete Natural Medicine Guide to 50 Most Common Medicinal Herbs, 2nd ed; Robert Rose Inc, 2004.
[50]
Parsons, W.T.; Cuthbertson, E.G. CSIRO.Noxious weeds of Australia; CSIRO Publishing: Collingwood, Vic, 2001.
[51]
Muhammad, B.; Khan, R.; Arshad, Y.; Khan, R.A. Phytochemical and cytotoxic analysis of Pharthenium hysterophosis selected from district Bannu, Pakistan. Afr. J. Biotechnol., 2012, 11, 11857-11860.
[52]
Amrehn, E.; Aschenbrenner, A.K.; Heller, A.; Spring, O. Localization of sesquiterpene lactone biosynthesis in cells of capitate glandular trichomes of Helianthus annuus (Asteraceae). Protoplasma, 2016, 253(2), 447-455.
[http://dx.doi.org/10.1007/s00709-015-0823-4]
[53]
Sobia, A.; Saadia, N.; Saira, K.; Rafique, A.M.; Ahmed, A.; Zahid, A. Bioherbicidal activity and metabolic profiling of potent allelopathic plant fractions against major weeds of wheat-way forward to lower the risk of synthetic herbicides. Front. Plant Sci., 2021, 12, 1-19.
[54]
Kumar, S.; Chashoo, G.; Saxena, A.K.; Pandey, A.K. Parthenium Hysterophorus: A probable source of anticancer, antioxidant and anti-HIV agents. BioMed Res. Int., 2013, e810734.
[55]
Bagchi, A.; Raha, A.; Mukherjee, P. A complete review on Parthenium Hysterophorus Linn. Int. J. Recent Adv. Pharm. Res., 2016, 6, 42-49.
[56]
Pandey, D.K. Allelochemicals in Parthenium in response to biological activity and the environment. Indian J. Weed Sci., 2009, 41, 111-123.
[57]
Amorim, M.H.R.; Gil da Costa, R.M.; Lopes, C.; Bastos, M.M. Sesquiterpene lactones: Adverse health effects and toxicity mechanisms. Crit. Rev. Toxicol., 2013, 43(7), 559-579.
[http://dx.doi.org/10.3109/10408444.2013.813905]
[58]
Picman, A.K.; Rodriguez, E.; Towers, G.H.N. Formation of adducts of parthenin and related sesquiterpene lactones with cysteine and glutathione. Chem. Biol. Interact., 1979, 28(1), 83-89.
[http://dx.doi.org/10.1016/0009-2797(79)90116-9]
[59]
Kamal, R.; Mathur, N. Histamine a biogenic amine from Parthenium Hysterophorus Linn. J. Phy. Res., 1991, 4, 213-221.
[60]
De la Fuente, J.R.; Uriburu, M.L.; Burton, G.; Sosa, V.E. Sesquiterpene lactone variability in Parthenium hystrophorus L. Phytochemistry, 2000, 55(7), 769-772.
[http://dx.doi.org/10.1016/S0031-9422(00)00288-0]
[61]
Kushwaha, V.; Maurya, S. Biological utilities of Parthenium Hysterophorus. J. Appl. Nat. Sci., 2012, 4(1), 137-143.
[http://dx.doi.org/10.31018/jans.v4i1.238]
[62]
Ulrichs, C.; Buettner, C.; Wiesner, M.; Roth, I.; Blievernicht, A.; Taye, T.; Mewis, I. Eco-physiological aspects of Parthenium weed (Parthenium Hysterophorus L.) management in Ethiopia. Acta Hortic., 2012, (937), 1173-1181.
[http://dx.doi.org/10.17660/ActaHortic.2012.937.147]
[63]
Das, B.; Reddy, V.S.; Krishnaiah, M.; Sharma, A.V.S.; Ravi, K.K.; Rao, J.V.; Sridhar, V. Acetylated pseudoguaianolides from Parthenium Hysterophorus and their cytotoxic activity. Phytochemistry, 2007, 68(15), 2029-2034.
[http://dx.doi.org/10.1016/j.phytochem.2007.05.002]
[64]
The Wealth of India. NISCOM, New Delhi., 2003, 4, 282-284.
[65]
Dubey, N.K.; Gupta, K.; Kheni, J.K.; Sinam, G.; Tomar, R.S.; Shasany, A.K.; Kumar, R.; Panigrahi, J.; Gupta, A.K. De novo transcriptome analysis of Parthenium Hysterophorus L. and insights into its potential uses. J. Res. Weed Sci, 2020, 3, 465-489.
[66]
Picman, A.K. Physilogical and chenmical activities of parthenium and other sesquiterpene lactones; University of British Colambia, 1977.
[67]
Lalita, K.A. Review on a weed Parthenium Hysterophorus (L.). Int. J. Curr. Res., 2018, 10, 17.
[68]
Rodríguez, E.; Dillon, M.O.; Mabry, T.J.; Mitchell, J.C.; Towers, G.H. Dermatologically active sesquiterpene lactones in trichomes of Parthenium Hysterophorus L. (Compositae). Experientia, 1976, 32(2), 236-238. a
[http://dx.doi.org/10.1007/BF01937785]
[69]
Ferrer, A.; Altabella, T.; Arro, M.; Boronat, A. Emerging roles for conjugated sterols in plants. Prog. Lipid Res., 2017, 67, 27-37.
[http://dx.doi.org/10.1016/j.plipres.2017.06.002]
[70]
Siddiqui, S.; Siddiqui, B.S.; Adil, Q.; Begum, S. Constituents of Mirabilis jalapa. Fitoterapia, 1990, 61, 471.
[71]
Kangsamaksin, T.; Chaithongyot, S.; Wootthichairangsan, C.; Hanchaina, R.; Tangshewinsirikul, C.; Svasti, J. Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth in mice via downregulation of tumor necrosis factor-α. PLoS One, 2017, 12(12), 12.
[http://dx.doi.org/10.1371/journal.pone.0189628]
[72]
Ma, X.; Wang, D.; Wu, Y.; Ho, R.J.Y.; Jia, L.; Guo, P.; Hu, L.; Xing, G.; Zeng, Y.; Liang, X-J. AIDS treatment with novel anti-HIV compounds improved by nanotechnology. AAPS J., 2010, 12(3), 272-278.
[http://dx.doi.org/10.1208/s12248-010-9187-z]
[73]
Chinsembu, K.C. Chemical diversity and activity profiles of hiv-1 reverse transcriptase inhibitors from plants. Rev. Bras. Farmacogn., 2019, 29(4), 504-528.
[http://dx.doi.org/10.1016/j.bjp.2018.10.006]
[74]
Vemuri, P.; Talluri, B.; Sirikonda, V.; Padigala, T.; Bodiga, V. Haematological and immunomodulatory evaluation of aqueous extract of Parthenium Hysterophorus leaves on wistar rats. Pharma Chem., 2016, 8, 441-444.
[75]
Kaur, M.; Gupta, K.B.; Thakur, S.; Kaur, S.; Dhiman, M. Parthenium Hysterophorus mediated inflammation and hyper-responsiveness via NF-KB pathway in human a549 lung cancer cell line. Environ. Toxicol., 2020, 35(11), 1241-1250.
[http://dx.doi.org/10.1002/tox.22989]
[76]
Vijayaraghavan, K.; Ashokkumar, T. Plant-mediated biosynthesis of metallic nanoparticles: A review of literature, factors affecting synthesis, characterization techniques and applications. J. Environ. Chem. Eng., 2017, 5(5), 4866-4883.
[http://dx.doi.org/10.1016/j.jece.2017.09.026]
[77]
Baky, N.A.; Amara, A.A.A.F. Recent approaches towards control of fungal diseases in plants: An updated review. J. Fungi (Basel), 2021, 7(11), 900.
[http://dx.doi.org/10.3390/jof7110900]
[78]
Rajiv, P.; Rajeshwari, S.; Venckatesh, R. Bio-fabrication of zinc oxide nanoparticles using leaf extract of Parthenium Hysterophorus L. and its size-dependent antifungal activity against plant fungal pathogens. Spectrochim. Acta A Mol. Biomol. Spectrosc., 2013, 112, 384-387.
[http://dx.doi.org/10.1016/j.saa.2013.04.072]
[79]
Ahsan, A.; Farooq, M.A.; Ahsan Bajwa, A.; Parveen, A. Green synthesis of silver nanoparticles using Parthenium Hysterophorus: Optimization, characterization and in vitro therapeutic evaluation. Molecules, 2020, 25(15), 3324.
[http://dx.doi.org/10.3390/molecules25153324]
[80]
Dwivedi, P.; Vivekanand, V.; Ganguly, R.; Singh, R.P. Parthenium Sp. as a plant biomass for the production of alkalitolerant xylanase from mutant Penicillium oxalicum SAUE-3.510 in submerged fermentation. Biomass Bioenergy, 2009, 33(4), 581-588.
[http://dx.doi.org/10.1016/j.biombioe.2008.09.001]
[81]
Sukanya, S.L.; Sudisha, J.; Hariprasad, P.; Niranjana, S.R.; Prakash, H.S.; Fathima, S.K. Antimicrobial activity of leaf extracts of Indian medicinal plants against clinical and phytopathogenic bacteria. Afr. J. Biotechnol., 2009, 8, 6677-6682.
[82]
Madan, H.; Gogia, S.; Sharma, S. Antimicrobial and spermicidal activities of Parthenium Hysterophorus Linn. and Alstonia scholaris Linn. Ind. J. Nat. Pro. Res, 2011, 2, 458-463.
[83]
Fazal, H.; Ahmad, N.; Ullah, I.; Inayat, H.; Abbasi, L. Antibacterial potential in Parthenium Hysterophorus, Stevia rebaudiana and Ginkgo biloba. Pak. J. Bot., 2011, 43, 1307-1313.
[84]
Tapwal, A. Nisha; Garg, S.; Gautam, N.; Kumar, R. In vitro. Antifungal potency of plant extracts against five phytopathogens. Braz. Arch. Biol. Technol., 2011, 54(6), 1093-1098.
[http://dx.doi.org/10.1590/S1516-89132011000600003]
[85]
Bashar, H.M.K.; Juraimi, A.S.; Ahmad-Hamdani, M.S.; Uddin, M.K.; Asib, N.; Anwar, M.P.; Rahaman, F. A mystic weed, Parthenium Hysterophorus: Threats, potentials and management. Agronomy (Basel), 2021, 11(8), 1514.
[http://dx.doi.org/10.3390/agronomy11081514]
[86]
Nyasembe, V.O.; Cheseto, X.; Kaplan, F.; Foster, W.A.; Teal, P.E.A.; Tumlinson, J.H.; Borgemeister, C.; Torto, B. The invasive american weed Parthenium Hysterophorus can negatively impact malaria control in Africa. PLoS One, 2015, 10(9), 9.
[http://dx.doi.org/10.1371/journal.pone.0137836]
[87]
Singh, A. Navneet, Ethnobotanical, pharmacological, antimicrobial potential and phytochemistry of Parthenium Hysterophorus Linn.: An update. Int. J. Toxicol. Pharmacol. Res., 2017, 9, 229-235.
[88]
Navie, S.C.; McFadyen, R.E.; Panetta, F.D.; Adkins, S.W. The biology of Australian weeds Parthenium Hysterophorus L. Plant Prot. Q., 1996, 11, 76-88.
[89]
Evans, H.C. Parthenium Hysterophorus: A review of its weed status and the possibilities for biological control. Bio News Info, 1997, 18, 10.
[90]
Birhanu, A.; Khan, P.R. The distribution, status and mitigation methods of Parthenium Hysterophorus L. in Ethiopia: A Review. J. Med. Plants Stud., 2018, 6, 05-10.
[91]
Sharma, V.K.; Sethuraman, G.; Bhat, R. Evolution of clinical pattern of parthenium dermatitis: A study of 74 cases. Contact Dermat., 2005, 53(2), 84-88.
[http://dx.doi.org/10.1111/j.0105-1873.2005.00652.x]
[92]
Nadeem, M.; Rani, Z.; Aman, S.; Kazmi, A.H.; Shabbir, A. Parthenium weed: A growing concern in Pakistan. J. Pak. Assoc. Dermatol., 2005, 15, 4-8.
[93]
Shashie, A.; Lisanework, N.; Tamado, T.; Steve, W. Impact of parthenium weed on the above-ground and soil seed bank communities of rangelands in Southeast Ethiopia. Int. Res. J. Agri. Sci. Soil Sci., 2013, 3, 262-274.
[94]
Khan, N.; Naveed, K.; Hussain, Z.; Alam Khan, S. Assessment of allelopathic effects of parthenium (Parthenium Hysterophorus L.) plant parts on seed germination and seedling growth of wheat (Triticum aestivum L.) cultivars. Pak. J. Weed Sci. Res., 2012, 18, 39-50.
[95]
Batish, D.R.; Singh, H.P.; Kohli, R.K.; Kaur, S.; Saxena, D.B.; Yadav, S. Assessment of phytotoxicity of parthenin. Z. Naturforsch. C Biosc., 2007, 62, 367-372.
[96]
Fang, C.; Zhihui, C. Research progress on the use of plant allelopaty in agriculture and the physiological and ecological mechanism of allelopathy. Front. Plant. Sci., 2015, 6, 1020.
[97]
Patil, B.J.; Khade, H.N. Allelopathic effect of Parthenium Hysterophorus L. extract on seed germination and seedling growth of Vignaaconitifolia (Jacq) Marechal an TrigonellafoenumgraecumL. Int. J. Res. Botany, 2015, 5, 6-8.
[98]
Shikha, R.; Jha, A. K. Leaf extract of Parthenium Hysterophorus L. affects the growth of Cajanuscajan (L.) Millsp. J of Res Agri Animal Sci., 2016, 4, 01-07.
[99]
Mao, R.; Shabbir, A.; Adkins, S. Parthenium Hysterophorus: A tale of global invasion over two centuries, spread and prevention measures. J. Environ. Manage., 2021, 279, 111751-111766.
[http://dx.doi.org/10.1016/j.jenvman.2020.111751]
[100]
Hassan, G.; Rashid, H.U.; Amin, A.; Khan, I.A.; Shehzad, N. Allelopathic Effect of Parthenium Hysterophorus on germination and growth of some important crops and weeds of economic importance. Planta Daninha, 2018, 36, 1-11.
[http://dx.doi.org/10.1590/s0100-83582018360100132]
[101]
Khan, M.S.; Ahmad, S. Pharmacognostical, phytochemical, biological and tissue culture studies on Parthenium Hysterophorus Linn: A review. Int J Alt Med., 2009, 6, 1-5.
[102]
Farooq, N.; Abbas, T.; Tanveer, A.; Jabran, K. Allelopathy for weed management.Co-Evolution of Secondary Metabolites.Reference Series in; Merillon, J.M.; Ramawat, K; Phytochemistry Springer,, , Ed.; Chan, 2020, pp. 505-519.

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