Survival Analysis Based on the Siddha Body Constitution of Asymptomatic SARS-CoV-2 Patients Under Integrative Management of Hydroxychloroquine (HCQ) and Kaba Sura Kudineer (KSK): A Retrospective Cross-sectional Case Series from Tirupati

Title:Survival Analysis Based on the Siddha Body Constitution of Asymptomatic SARS-CoV-2 Patients Under Integrative Management of Hydroxychloroquine (HCQ) and Kaba Sura Kudineer (KSK): A Retrospective Cross-sectional Case Series from Tirupati

Volume: 7 Issue: 6

Author(s): Samraj Karunanithi*, Sreenivasa Rao P, K Nandhagopal, Manoj Kumar D., N.P. Vinod, P. Sathyarajeswaran and K. Kanakavalli

Affiliation:

• Siddha Clinical Research Unit, Central Council for Research in Siddha, Tirupati,India

Keywords: Body constitution, COVID-19, hydroxychloroquine, novel coronavirus, siddha medicine, yakkai ilakkanam.

Abstract: Background: The present study analysed the impact of the integrated medical care of hydroxychloroquine (HCQ) and Siddha herbal preparation KSK on asymptomatic COVID-19 patients based on their body constitution.

Objective: The present study aimed to analyse the duration of the hospital stay of asymptomatic COVID-19 patients treated with the integrated medical care of hydroxychloroquine (HCQ) and herbal decoction of Kaba Sura Kudineer (KSK).

Design: The study included a retrospective case series of 19 asymptomatic confirmed SARS-Cov- -2 patients from District COVID Care Centre, Tirupati, India, between 23rd May to 7th June 2020.

Methods: Clinical data were collected using a standardised case report form containing demographic information, length of hospital stays, and Siddha Yakkai Ilakkanam (body constitution) from the records. The association between the length of hospital stay, age, gender, and Siddha YI for the confirmed patients after admission was analysed by the Kaplan Meier survival analysis method.

Results: Patients belonging to the Aiyam group stayed for at least nine days in the hospital, and 80% took ten or more days to cure the disease. About 71.4% took more than four days and three days of hospital stay in the Azhal and Vali groups, respectively. It was observed that 75% of females and 73.3% of males took nine days or more of hospital stay, respectively. The range of hospital stay was between 2-15 days for patients aged between 19 – 40 years.

Conclusion: The present study explored the significance of integrating Siddha medicine with Western medicine in the management of SARS Cov-2 infection. An overall median of 9 days in the length of stay and 8.5 days in the overall mean survival time was documented. The patients of the present study on integrative treatment recovered about nine days earlier in comparison to the patients studied in Vietnam and China.

Cite this article as:

Karunanithi Samraj*, P Rao Sreenivasa, Nandhagopal K , D. Kumar Manoj , Vinod N.P. , Sathyarajeswaran P. and Kanakavalli K. , Survival Analysis Based on the Siddha Body Constitution of Asymptomatic SARS-CoV-2 Patients Under Integrative Management of Hydroxychloroquine (HCQ) and Kaba Sura Kudineer (KSK): A Retrospective Cross-sectional Case Series from Tirupati, Current Traditional Medicine 2021; 7 (6) : e100821195485 . https://dx.doi.org/10.2174/2215083807666210810113120