Abstract
Coumarin is a heterocyclic scaffold and its derivatives, namely Schiff bases, esters, and hydrazides, etc., play an important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological activities like antifungal, antimicrobial, antiviral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, antiaflatoxigenic, analgesics, antioxidant and Oestrogenic, etc., have been analyzed. This review covers the latest literature and knowledge on the synthetic procedures for various coumarin and its derivatives, their biological and pharmacological applications.
Keywords: Coumarin, Synthesis, derivatives, Biological activities, heterocyclic compounds, benzo-β-pyrone.
Graphical Abstract
Letters in Organic Chemistry
Title:Overview of Coumarins and its Derivatives: Synthesis and Biological Activity
Volume: 18 Issue: 11
Author(s): Tanvi Sahni, Sunita Sharma*, Diksha Verma and Pardeep Kaur
Affiliation:
- Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana,India
Keywords: Coumarin, Synthesis, derivatives, Biological activities, heterocyclic compounds, benzo-β-pyrone.
Abstract: Coumarin is a heterocyclic scaffold and its derivatives, namely Schiff bases, esters, and hydrazides, etc., play an important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological activities like antifungal, antimicrobial, antiviral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, antiaflatoxigenic, analgesics, antioxidant and Oestrogenic, etc., have been analyzed. This review covers the latest literature and knowledge on the synthetic procedures for various coumarin and its derivatives, their biological and pharmacological applications.
Export Options
About this article
Cite this article as:
Sahni Tanvi , Sharma Sunita *, Verma Diksha and Kaur Pardeep , Overview of Coumarins and its Derivatives: Synthesis and Biological Activity, Letters in Organic Chemistry 2021; 18 (11) . https://dx.doi.org/10.2174/1570178617999201006195742
DOI https://dx.doi.org/10.2174/1570178617999201006195742 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Mechanisms of Protective Effects of SGLT2 Inhibitors in Cardiovascular Disease and Renal Dysfunction
Current Topics in Medicinal Chemistry Immunotherapy for Prostate Cancer
Current Pharmaceutical Design Strategies for Non-Invasive Molecular Imaging of Acute Allograft Rejection by Gamma Scintigraphy and Positron Emission Tomography
Current Radiopharmaceuticals Nutritional Aspects Relating to the Developmental Origins of Health and Disease
Current Women`s Health Reviews Annotation of the Human Genome by High-Throughput Sequence Analysis of Naturally Occurring Proteins
Current Proteomics The Nutrigenetics and Pharmacogenetics of Vitamin D Pathways
Current Pharmacogenomics and Personalized Medicine The Use of Nimesulide and Its Analogues in Cancer Chemoprevention
Anti-Cancer Agents in Medicinal Chemistry The Cancer Related Thrombotic Tendency in Sepsis
Current Drug Targets Heparin - a Key Drug in the Treatment of the Circulatory Degenerative Diseases: Controlling its Action with Polymers
Current Pharmaceutical Design Past and Recent Progress of Molecular Imaging Probes for β-Amyloid Plaques in the Brain
Current Medicinal Chemistry Cysteine-Rich Mini-Proteins in Human Biology
Current Topics in Medicinal Chemistry Gestational Programming of Offspring Obesity: A Potential Contributor to Alzheimers Disease
Current Alzheimer Research PI3K/AKT/mTOR Inhibitors In Ovarian Cancer
Current Medicinal Chemistry Type 2 Diabetes Mellitus and the Elderly: An Update on Drugs Used to Treat Glycaemia
Current Vascular Pharmacology Iron Chelators: Development of Novel Compounds with High and Selective Anti-Tumour Activity
Current Drug Delivery Human Serum Albumin Conjugated Biomolecules for Cancer Molecular Imaging
Current Pharmaceutical Design Advances in the Discovery of cis-Regulatory Elements
Current Bioinformatics In-Situ Hybridization as a Molecular Tool in Cancer Diagnosis and Treatment
Current Medicinal Chemistry The Central Role of Angiotensin I-Converting Enzyme in Vertebrate Pathophysiology
Current Topics in Medicinal Chemistry Comparative Proteomics of Liver of the Diabetic Obese db/db and Non-Obese or Diabetic Mice
Current Proteomics