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Review Article

用于癌症治疗的纳米载体给药系统：十年回顾

卷 28, 期 19, 2021

发表于: 05 October, 2020

页: [3753 - 3772] 页: 20

弟呕挨: 10.2174/0929867327666201005111722

价格: $65

摘要

近年来，由于常规化疗生物利用度差、治疗指数低、副作用不明等缺点，癌症研究的重点转移到了化疗药物的新型纳米载体上。通过使用可生物降解的材料，纳米载体通常具有良好的生物相容性、副作用低、靶向性、控制释放特性和提高功效的优点。更重要的是，基于纳米载体的抗癌药物递送系统清楚地显示出克服与常规化疗相关的问题的潜力。为了促进这一领域的深入研究和发展，我们在此总结和分析了用于癌症治疗的各种基于纳米载体的药物递送系统，包括概念、类型、特征和制备方法。还包括癌症治疗的主动和被动靶向机制，并简要介绍了近十年来用于抗癌药物传递的纳米载体的研究进展。

关键词: 纳米载体，癌症化疗，药物传递系统，靶向机制，治疗，应用。

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