摘要
癫痫病是中枢神经系统最常见的疾病之一。尽管癫痫病在世界范围内很普遍,但大约80%的癫痫病患者住在发展中国家或中低收入国家。直到20世纪第二个十年,癫痫病主要通过传统疗法治疗。如今,抗癫痫药已被用作预防和控制癫痫发作的一般疗法。但是,由于其国家的医疗保健系统和许多其他原因,例如文化,社会人口统计学和经济贫困,阻碍了患者使用这些药物。此外,大约30-40%的癫痫患者患有难治性癫痫,此外,AED具有不良副作用,可能导致治疗失败或降低患者的生活质量。尽管最近在癫痫治疗方面取得了进步,但是仍然需要改善医学治疗,特别是在功效,安全性和可及性上。由于草药已经在世界范围内使用了多个世纪来治疗癫痫病,因此,对各种物种和起源的植物中草药和植物化学成分进行严格研究可能会导致发现新型AED,这似乎是有道理的。如今,已经确定了在世界不同文化和地区使用的许多药用植物。这些植物的大多数植物化学成分已被鉴定,在某些情况下还可以确定其靶标。因此,有可能可以从药用植物中获得新的,有效的和容易获得的抗惊厥药。
关键词: 癫痫,癫痫发作,点燃,抗癫痫药,植物化学物质,草药。
图形摘要
Current Drug Targets
Title:Herbal Medicine in the Treatment of Epilepsy
Volume: 22 Issue: 3
关键词: 癫痫,癫痫发作,点燃,抗癫痫药,植物化学物质,草药。
摘要: Epilepsy is one of the most common disorders of the central nervous system. Although epilepsy is common worldwide, approximately 80% of epileptic patients live in the developing countries or those with low-middle income. Up until the second decade of the 20th century, epilepsy was treated mostly by traditional remedies. Today, antiepileptic drugs are used as a general treatment instead to prevent and control epileptic seizures. However, patient access to these drugs is hindered due to the healthcare systems of their countries and a number of other reasons, such as cultural, socio-demographic, and financial poverty. In addition, approximately 30-40%of epileptic patients suffer from refractory epilepsy, additionally, AEDs have adverse side-effects that can lead to treatment failure or reduce the patient’s quality of life. Despite recent advances in the treatment of epilepsy, there is still a need for improving medical treatment with a particular focus on efficacy, safety, and accessibility. Since herbal medicines have been used for many centuries around the world for treating epilepsy, it is, therefore, plausible that a rigorous study on herbal medicine and phytochemical components within plants of various species and origin may lead to the discovery of novel AEDs. Nowadays, many medicinal plants used in different cultures and regions of the world have been identified. Most phytochemical components of these plants have been identified and, in some cases, their targets located. Therefore, it is possible that new, effective, and accessible anticonvulsants drugs can be obtained from a medicinal plant.
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Cite this article as:
Herbal Medicine in the Treatment of Epilepsy, Current Drug Targets 2021; 22 (3) . https://dx.doi.org/10.2174/1389450121999201001152221
DOI https://dx.doi.org/10.2174/1389450121999201001152221 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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