Abstract
Benzazepine, a seven membered aza-heterocyclic ring fused with aromatic unit, is involved in research aimed to evaluate new products that possess interesting biological activities. The aim of this review is to provide an overview of the diverse and important pharmacological activities of benzazepine moiety. This review highlights importance of benzazepine derivatives as anti-depressant, anti-hypertensive, anti-ischaemic, anorectic, anti-histamine agents, AChE inhibitor, TRPV1 antagonist and also in the treatment of hyponatremia. Recent efforts made to discover various pharmacologically active molecules that contain benzazepine moiety are also reported.
Keywords: Benzazepine analogues, inhibitors, pharmacological activity, receptors.
Graphical Abstract
Current Bioactive Compounds
Title:Pharmacological and Biological Activities of Benzazepines: An Overview
Volume: 11 Issue: 3
Author(s): Jigar H. Shah, Rama M. Hindupur and Hari N. Pati
Affiliation:
Keywords: Benzazepine analogues, inhibitors, pharmacological activity, receptors.
Abstract: Benzazepine, a seven membered aza-heterocyclic ring fused with aromatic unit, is involved in research aimed to evaluate new products that possess interesting biological activities. The aim of this review is to provide an overview of the diverse and important pharmacological activities of benzazepine moiety. This review highlights importance of benzazepine derivatives as anti-depressant, anti-hypertensive, anti-ischaemic, anorectic, anti-histamine agents, AChE inhibitor, TRPV1 antagonist and also in the treatment of hyponatremia. Recent efforts made to discover various pharmacologically active molecules that contain benzazepine moiety are also reported.
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Cite this article as:
H. Shah Jigar, Hindupur Rama M. and N. Pati Hari, Pharmacological and Biological Activities of Benzazepines: An Overview, Current Bioactive Compounds 2015; 11 (3) . https://dx.doi.org/10.2174/1573407211666150910202200
DOI https://dx.doi.org/10.2174/1573407211666150910202200 |
Print ISSN 1573-4072 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6646 |
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