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Current Rheumatology Reviews

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ISSN (Print): 1573-3971
ISSN (Online): 1875-6360

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Review Article

Quantitative Sensory Testing Protocols to Evaluate Central and Peripheral Sensitization in Knee OA: A Protocol for a Scoping Review

Author(s): Benjamin Rudy-Froese, Jonathan Rankin , Curtis Hoyt, Keenu Ramsahoi, Liam Gareau, William Howatt and Lisa C. Carlesso *

Volume 17, Issue 1, 2021

Published on: 07 September, 2020

Page: [76 - 80] Pages: 5

DOI: 10.2174/1573397116666200907113755

Price: $65

Abstract

Background: Quantitative sensory testing (QST) methods have become widely used for the assessment of nervous system sensitization to nociceptive signalling in studies of people with knee osteoarthritis (OA). However, few standardised QST protocols have been developed. Variability in their execution may lead to differences in their interpretation.

Objective: The proposed scoping review will seek to identify various QST methodologies being used in the assessment of sensitization and how sensitization is being defined in people with knee OA.

Methods and Analysis: This scoping review will be guided by existing scoping review methodologies. Relevant studies will be extracted from the following electronic databases: Medical Literature Analysis and Retrieval System Online, ExcerptaMedica Database, Allied and Complementary Medicine Database and the Cumulative Index to Nursing Allied Health Literature. Independent screening of the abstracts and full articles and data extraction will be performed in pairs. Information extracted will focus on qualitative and quantitative data relevant to the content of the protocols from included studies. Data will be summarised in order to draw conclusions on the common elements used in QST protocols and definitions of sensitization for knee OA.

Conclusion: This scoping review will provide insight into the most common methods of QST used in the assessment of nociceptive signaling in people with knee OA. This will potentially identify areas where a systematic review or other primary research may be required in order to develop fixed evidence-based protocols for QST in patients with knee OA.

Keywords: Pain, quantitative sensory testing, sensitization, knee osteoarthritis, protocol, scoping review.

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[1]
Jinks C, Jordan K, Croft P. Osteoarthritis as a public health problem: The impact of developing knee pain on physical function in adults living in the community: (KNEST 3). Rheumatology 2007; 46(5): 877-81.
[http://dx.doi.org/10.1093/rheumatology/kem013] [PMID: 17308312]
[2]
Dieppe PA, Lohmander LS. Pathogenesis and management of pain in osteoarthritis. Lancet 2005; pp. 965-73.
[3]
Courtney CA, O’Hearn MA, Hornby TG. Neuromuscular function in painful knee osteoarthritis. Curr Pain Headache Rep 2012; 16(6): 518-24.
[http://dx.doi.org/10.1007/s11916-012-0299-2] [PMID: 23054978]
[4]
Fingleton C, Smart K, Moloney N, Fullen BM, Doody C. Pain sensitization in people with knee osteoarthritis: A systematic review and meta-analysis. Osteoarthritis Cartilage 2015; 23(7): 1043-56.
[http://dx.doi.org/10.1016/j.joca.2015.02.163] [PMID: 25749012]
[5]
Felson DT. The sources of pain in knee osteoarthritis. Curr Opin Rheumatol 2005; 17(5): 624-8.
[http://dx.doi.org/10.1097/01.bor.0000172800.49120.97] [PMID: 16093843]
[6]
Schaible HG. Mechanisms of chronic pain in osteoarthritis.Springer In: 2012; 14: pp. 549-6.
[http://dx.doi.org/10.1007/s11926-012-0279-x]
[7]
Bedson J, Croft PR. The discordance between clinical and radiographic knee osteoarthritis: A systematic search and summary of the literature. BMC Musculoskelet Disord 2008; 9: 116.
[http://dx.doi.org/10.1186/1471-2474-9-116] [PMID: 18764949]
[8]
Arendt-Nielsen L, Nie H, Laursen MB, et al. Sensitization in patients with painful knee osteoarthritis. Pain 2010; 149(3): 573-81.
[http://dx.doi.org/10.1016/j.pain.2010.04.003] [PMID: 20418016]
[9]
Suokas AK, Walsh DA, McWilliams DF, et al. Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis. Osteoarthritis Cartilage 2012; 20(10): 1075-85.
[http://dx.doi.org/10.1016/j.joca.2012.06.009] [PMID: 22796624]
[10]
Arendt-Nielsen L, Yarnitsky D. Experimental and clinical applications of quantitative sensory testing applied to skin, muscles and viscera. J Pain 2009; 10(6): 556-72.
[http://dx.doi.org/10.1016/j.jpain.2009.02.002] [PMID: 19380256]
[11]
Pavlaković G, Petzke F. The role of quantitative sensory testing in the evaluation of musculoskeletal pain conditions. Curr Rheumatol Rep 2010; 12(6): 455-61.
[http://dx.doi.org/10.1007/s11926-010-0131-0] [PMID: 20857243]
[12]
Uddin Z, Macdermid JC. Quantitative sensory testing in chronic musculoskeletal pain. 2016. Available from: http://www.ncbi.nlm. nih.gov/pubmed/26893116
[13]
Maier C, Baron R, Tölle TR, Binder A, Birbaumer N, Birklein F, et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. Pain 2010; 150(3): 439-50.
[14]
Lluch E, Torres R, Nijs J, Van Oosterwijck J. Evidence for central sensitization in patients with osteoarthritis pain: A systematic literature review. European Journal of Pain 2014; 1367-75.
[15]
O’Neill TW, Felson DT. Mechanisms of osteoarthritis (OA) pain. Curr Osteoporos Rep 2018; 16(1): 611-6.
[16]
Syx D, Tran PB, Miller RE, Malfait AM. Peripheral mechanisms contributing to osteoarthritis pain. Curr Rheumatol Rep 2018; 20(2): 9.
[17]
Halas G, Schultz ASH, Rothney J, Goertzen L, Wener P, Katz A. A scoping review protocol to map the research foci trends in tobacco control over the last decade. BMJ Publishing Group 2015; 5
[http://dx.doi.org/10.1136/bmjopen-2014-006643]
[18]
Levac D, Colquhoun H, O’Brien KK. Scoping studies: Advancing the methodology. Implement Sci 2010; 5(1): 69.
[http://dx.doi.org/10.1186/1748-5908-5-69] [PMID: 20854677]
[19]
Moher D, Liberati A, Tetzlaff J, Altman DG, Altman D, Antes G, et al. PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Med 2009; 6(7): e1000097.
[http://dx.doi.org/10.1371/journal.pmed.1000097] [PMID: 19621072]
[20]
Cochrane Collaboration. Data collection form for intervention reviews: RCTs only (Version 3). 2014. Available from: https://dplp.cochrane.org/data-extraction-forms

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