General Review Article

慢性创伤治疗的挑战和新方法

卷 21, 期 12, 2020

页: [1264 - 1275] 页: 12

弟呕挨: 10.2174/1389450121666200623131200

价格: $65

摘要

据估计,慢性未愈合伤口每年要花费美国医疗保健部门280 - 310亿美元。糖尿病性溃疡、动脉性和静脉性溃疡以及压疮是一些最常见的慢性伤口类型。由于目前肥胖和糖尿病的流行以及人口中老年人的增加,慢性伤口的负担继续增加,老年人比年轻人更容易受到慢性伤口的伤害。这些患者群体也极易受到机会性和耐多药病原体引起的使人衰弱的感染。微循环减少、促进伤口愈合的细胞因子和生长因子的可用性降低、耐多药和形成生物膜的微生物的感染是导致慢性未愈合伤口发展的一些关键因素。本文讨论了了解慢性伤口病理的新方法和改善慢性伤口护理的方法,特别是当慢性伤口感染耐多药、形成生物膜的微生物时。

关键词: 慢性伤口、感染、肥胖流行、生物膜、细胞因子、病原体

图形摘要

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