Search Result "leadlikeness"


Failure and Success in Modern Drug Discovery: Guiding Principles in the Establishment of High Probability of Success Drug Discovery Organizations

Journal: Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2005 Page: 519-527
Author(s): G. M. Rishton

In Silico Technology for Identification of Potentially Toxic Compounds in Drug Discovery

Journal: Current Computer-Aided Drug Design
Volume: 2 Issue: 2 Year: 2006 Page: 95-103
Author(s): Remigijus Didziapetris, Derek P. Reynolds, Pranas Japertas, Donatas Zmuidinavicius, Alanas Petrauskas

Research Article

Reduced Level of Prolylhydroxyproline in the Nail Clippings of Oral CancerPatients and its Role as an Activator of Phospholipase C-β2

Journal: Current Protein & Peptide Science
Volume: 24 Issue: 8 Year: 2023 Page: 684-699
Author(s): Ajay Kumar Raj,Kiran B. Lokhande,Sachin C. Sarode,Nilesh Kumar Sharma

Strategies for Compound Selection

Journal: Current Drug Discovery Technologies
Volume: 1 Issue: 3 Year: 2004 Page: 211-220
Author(s): Marius M. Olah, Cristian G. Bologa, Tudor I. Oprea

Discovery of New Potential Antimalarial Compounds Using Virtual Screening of ZINC Database

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 18 Issue: 2 Year: 2015 Page: 227-234
Author(s): Jahan B. Ghasemi,Fereshteh Shiri,Somayeh Pirhadi,Zahra Heidari

open access plus

Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies

Journal: Current Alzheimer Research
Volume: 12 Issue: 9 Year: 2015 Page: 814-828
Author(s): Marcus Pickhardt,Thomas Neumann,Daniel Schwizer,Kari Callaway,Michele Vendruscolo,Dale Schenk,Peter St. George-Hyslop,Eva M. Mandelkow,Christopher M. Dobson,Lisa McConlogue,Eckhard Mandelkow,Gergely Toth

Nature Bank and the Queensland Compound Library: Unique International Resources at the Eskitis Institute for Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 17 Issue: 3 Year: 2014 Page: 201-209
Author(s): David Camp,Stuart Newman,Ngoc B. Pham,Ronald J. Quinn

Research Article

Synthesis and In-silico Identification of New Bioactive 1,3,4-oxadiazole Tagged 2,3-dihydroimidazo[1,2-a]pyridine Derivatives

Journal: Current Bioactive Compounds
Volume: 17 Issue: 4 Year: 2021 Page: 318-330
Author(s): Bhagwat S. Jadhav,Vipul P. Purohit,Ramesh S. Yamgar,Rajesh S. Kenny,Suraj N. Mali,Hemchandra K. Chaudhari,Mustapha C. Mandewale

Research Article

Synthesis and Molecular Docking of Some Novel Thiazoles and Thiadiazoles Incorporating Pyranochromene Moiety as Potent Anticancer Agents

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1670-1682
Author(s): Sobhi M. Gomha,Abdou O. Abdelhamid,Omaima M. Kandil,Saher M Kandeel,Nadia A Abdelriheem

Research Article

Lead Molecule Prediction and Characterization for Designing MERS-CoV 3C-like Protease Inhibitors: An In silico Approach

Journal: Current Computer-Aided Drug Design
Volume: 15 Issue: 1 Year: 2019 Page: 82-88
Author(s): Md. Mostafijur Rahman,Md. Bayejid Hosen,M. Zakir Hossain Howlader,Yearul Kabir

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