Search Result "active kinase conformation"

New Insights in Protein Kinase Conformational Dynamics

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 17 Year: 2012 Page: 1889-1895
Author(s): Giorgio Saladino,Francesco Luigi Gervasio

Targeting Protein Multiple Conformations: A Structure-Based Strategy for Kinase Drug Design

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1394-1407
Author(s): Liao Jie-Lou Jeffrey, Andrews C. Robert

Small Molecule Inhibitors of Protein Kinases in Cancer- How to Overcome Resistance

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 1101-1110
Author(s): R. Griffith, M. N. Brown, A. McCluskey, L. K. Ashman

Tyrosine Kinase Mutations in Human Cancer

Journal: Current Molecular Medicine
Volume: 7 Issue: 1 Year: 2007 Page: 77-84
Author(s): Ernst Lengyel, Kenjiro Sawada, Ravi Salgia

Targeting RhoA/Rho Kinase and p21-Activated Kinase Signaling to Prevent Cancer Development and Progression

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 4 Issue: 2 Year: 2009 Page: 110-124
Author(s): Yu-Wen E. Chang, Ronald R. Bean, Rolf Jakobi

AMP-Activated Protein Kinase: Structure and Regulation

Journal: Current Protein & Peptide Science
Volume: 9 Issue: 5 Year: 2008 Page: 478-492
Author(s): Pascual Sanz

Review Article

The Use of Conformational Restriction in Medicinal Chemistry

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 19 Year: 2019 Page: 1712-1733
Author(s): Pedro de Sena M. Pinheiro,Daniel A. Rodrigues,Rodolfo do Couto Maia,Sreekanth Thota,Carlos A.M. Fraga

Natural Products as a Source of Protein Kinase Activators and Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1333-1339
Author(s): Andrew Marston

Polo-Like Kinases Inhibitors

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 2 Year: 2012 Page: 3937-3948
Author(s): L. Garuti, M. Roberti, G. Bottegoni

Letter Article

Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry

Journal: Protein & Peptide Letters
Volume: 28 Issue: 5 Year: 2021 Page: 481-488
Author(s): Min Woo Yun,Kiae Kim,Ji Young Park,Ka Young Chung

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