Search Result "S1 subsite"

Importance of Amino Acids, Gln-119 and Tyr-376, in the S1 Pocket of Escherichia coli Peptidase N in Determining Substrate Specificity

Journal: Protein & Peptide Letters
Volume: 23 Issue: 6 Year: 2016 Page: 548-561
Author(s): Mrinmoy Das,Manoj Bhosale,Nitin Wadhwa,Syed M. Ahmed,Chetana Bhaskarla,Anujith Kumar,Narayanaswamy Srinivasan,Dipankar Nandi

Mapping of the Active Site of Proteases in the 1960s and Rational Design of Inhibitors/Drugs in the 1990s

Journal: Current Protein & Peptide Science
Volume: 6 Issue: 6 Year: 2005 Page: 501-512
Author(s): I. Schechter

Dipeptide Inhibitors of Thermolysin and Angiotensin I-Converting Enzyme

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 16 Year: 2012 Page: 1748-1762
Author(s): Mahmud Tareq Hassan Khan,Kenichi Dedachi,Toshiro Matsui,Noriyuki Kurita,Monica Borgatti,Roberto Gambari,Ingebrigt Sylte

Probing Proteinase Active Sites Using Oriented Peptide Mixture Libraries - ADAM-10

Journal: Letters in Drug Design & Discovery
Volume: 1 Issue: 1 Year: 2004 Page: 6-13
Author(s): John L. Krstenansky, Jihong Wang, Gregg R. Chenail, Matthew R. Tiffany, Geoffrey M. Kuesters, Barbara C. Natke, John J. Nestor, Jr.

Interaction of EGLIN C Variants with the Extended Subsites of the Precursor Processing Proteases*.

Journal: Protein & Peptide Letters
Volume: 12 Issue: 5 Year: 2005 Page: 415-420
Author(s): Tomoko Komiyama

Structural Elements of Ligand Recognition Site in Secretory Phospholipase A2 and Structure-Based Design of Specific Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 8 Year: 2007 Page: 757-764
Author(s): Nagendra Singh, Rishi K. Somvanshi, Sujata Sharma, Sharmistha Dey, Punit Kaur, Tej P. Singh

Research Article

Computational Analysis of Physicochemical Factors Driving CYP2D6 Ligand Interaction

Journal: Current Computer-Aided Drug Design
Volume: 13 Issue: 1 Year: 2017 Page: 39-47
Author(s): Olujide O. Olubiyi, Maryam O. Olagunju, Abiola O. Obisesan

Unraveling Sub-Site Specificities of Peptidic Serine Protease Inhibitors by Substitutional and Structural Analysis

Journal: Protein & Peptide Letters
Volume: 12 Issue: 5 Year: 2005 Page: 449-456
Author(s): Wolfgang Hohne, Kai Hilpert

Entering the Era of Non-Basic P1 Site Groups: Discovery of Xarelto™ (Rivaroxaban)

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 3 Year: 2010 Page: 257-269
Author(s): Alexander Straub, Susanne Roehrig, Alexander Hillisch

Matrix Metalloproteinase Inhibitors: A Review on Pharmacophore Mapping and (Q)Sars Results

Journal: Current Medicinal Chemistry
Volume: 12 Issue: 3 Year: 2005 Page: 339-355
Author(s): C. A. Kontogiorgis, P. Papaioannou, D. J. Hadjipavlou-Litina

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