Search Result "IVIVE"

Quantitative Prediction of Glucuronidation in Humans Using the In Vitro- In Vivo Extrapolation Approach

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 11 Year: 2013 Page: 1343-1352
Author(s): Baojian Wu,Dong Dong,Ming Hu,Shuxing Zhang

Impact of Input Parameters on the Prediction of Hepatic Plasma Clearance Using the Well-Stirred Model

Journal: Current Drug Metabolism
Volume: 11 Issue: 7 Year: 2010 Page: 583-594
Author(s): Hong Wan, Peter Bold, Lars-Olof Larsson, Johan Ulander, Sheila Peters, Boel Lofberg, Anna-Lena Ungell, Mats Nagard, Antonio Llinas

Human-Based In Vitro Experimental Systems for the Evaluation of Human Drug Safety

Journal: Current Drug Safety
Volume: 2 Issue: 3 Year: 2007 Page: 193-199
Author(s): Albert P. Li

Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat

Journal: Drug Metabolism Letters
Volume: 10 Issue: 2 Year: 2016 Page: 91-100
Author(s): Peter W. Fan, Jacob Z. Chen, M. Allan Jaochico, Hank La, Ning Liu, Teresa Mulder, Robert T. Cass, Matthew Durk, Kirsten Messick, Nicole Valle, Shannon Liu, Wendy Lee, James J. Crawford, Joachim Rudolf, Lesley J. Murray, S. Cyrus Khojasteh, Matthew Wright

Opinion Article

Evaluating Lean Liver Volume as a Potential Scaler for In Vitro-In Vivo Extrapolation of Drug Clearance in Obesity Using the Model Drug Antipyrine

Journal: Current Drug Metabolism
Volume: 21 Issue: 10 Year: 2020 Page: 746-750
Author(s): Jaydeep Sinha,Stephen B. Duffull,Bruce Green,Hesham S. Al-Sallami

Evaluation of Human Pharmacokinetics, Therapeutic Dose and Exposure Predictions Using Marketed Oral Drugs

Journal: Current Drug Metabolism
Volume: 8 Issue: 5 Year: 2007 Page: 463-479
Author(s): D.F. McGinnity, J. Collington, R.P. Austin, R.J. Riley

Research Article

In vitro Measurement and In vivo Prediction of Time-Dependent Inhibitory Effects of Three Tyrosine Kinase Inhibitors on CYP3A Activity

Journal: Current Drug Metabolism
Volume: 22 Issue: 10 Year: 2021 Page: 802-810
Author(s): Liyan Wang,Tingting Zhao,Yunxiang Wang,Banglian Hu,Jianfei Tao,Jinshan Ke,Tingfei Wei,Guangbo Ge,Qiang Meng,Changyuan Wang,Qi Liu,Huijun Sun,Jingjing Wu,Yanwei Chen

Research Article

Avapritinib Carries the Risk of Drug Interaction via Inhibition of UDP-Glucuronyltransferase (UGT) 1A1

Journal: Current Drug Metabolism
Volume: 25 Issue: 3 Year: 2024 Page: 197-204
Author(s):

Multifunctional Porous Silicon for Therapeutic Drug Delivery and Imaging

Journal: Current Drug Discovery Technologies
Volume: 8 Issue: 3 Year: 2011 Page: 228-249
Author(s): Helder A. Santos, Luis M. Bimbo, Vesa-Pekka Lehto, Anu J. Airaksinen, Jarno Salonen, Jouni Hirvonen

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