Abstract
InsP6 with or without inositol enhances NK cell activity and stimulates polymorphonuclear cell priming function and the macrophages to produce cytokines. InsP6 can inhibit human immunodeficiency virus (HIV) replication; both InsP5 and InsP6 are critical in HIV particle assembly. InsP6 plays significant roles in mucosal protection in the gastrointestinal tract, and inflammation.
Keywords: Asbestosis, gastric ulcer, granzymes, HIV, macrophage, natural killer, NK cells, perforin, polymorphonuclear cells.
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Cite this chapter as:
A.K.M. Shamsuddin, Guang-Yu Yang ;Roles of Inositol & Inositol Phosphates in Immunity, Infection and Inflammation, Inositol & its Phosphates: Basic Science to Practical Applications (2015) 1: 216. https://doi.org/10.2174/9781681080079115010019
DOI https://doi.org/10.2174/9781681080079115010019 |
Publisher Name Bentham Science Publisher |