Abstract
Functions that potentially can be performed by secreted mucins have been analyzed by bioinformatics using the Motifscan and Eukaryotic Linear Motif (ELM) tools and STRING 9.0 interaction network. A number of potentially important motifs were discovered and possible functional partners of the secreted mucin glycoproteins were predicted. A new role of galactin-3 in physiological transformation of the intestinal mucus gel layers is proposed.
Keywords: Secreted mucins, galectin-3, bioinformatics.
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Cite this chapter as:
Joseph Z. Zaretsky, Daniel H. Wreschner ;Secreted Mucins: Covert Functions, Mucins – Potential Regulators of Cell Functions Volume Title: Gel-Forming and Soluble Mucins (2013) 1: 547. https://doi.org/10.2174/9781608054541113010015
DOI https://doi.org/10.2174/9781608054541113010015 |
Print ISSN 2589-2983 |
Publisher Name Bentham Science Publisher |
Online ISSN 2214-0824 |