Vitamin D - A Novel Therapy for Chronic Diseases?

Vitamin D and Pregnancy

Author(s): Shaikha Alnaqbi*, Reem El Asmar, Russul AlQutub, Alyaa Masaad, Noor Abu Dheir, Salma Abu Qiyas and Dimitrios Papandreou

Pp: 109-119 (11)

DOI: 10.2174/9789815305333124010011

* (Excluding Mailing and Handling)

Abstract

Vitamin D insufficiency is prevalent among pregnant women and infants worldwide. Expectant mothers with a heightened risk of vitamin D deficiency may have notably low levels of 25-hydroxyvitamin D (25(OH)D) in their newborns, raising the likelihood of nutritional rickets. Numerous observational studies suggest a link between inadequate vitamin D levels during pregnancy and various adverse perinatal outcomes such as hypertensive disorders (like preeclampsia), restricted fetal growth, and premature birth. Nevertheless, the limited number of large-scale randomized controlled trials (RCTs) conducted so far have produced conflicting findings regarding the effectiveness of vitamin D supplementation in enhancing perinatal outcomes. 

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