Biomedical Applications of Perovskites: The Era of Bio-Piezoelectric Systems

Bone Regeneration and Bone Growth Using Perovskites

Author(s): A.J. Pavithra, S.D. Anudevi, G.S. Hikku* and K. Kumar Ebenezar

Pp: 154-174 (21)

DOI: 10.2174/9789815256383124010011

* (Excluding Mailing and Handling)

Abstract

 Perovskite materials are becoming more popular in biomedical applications, notably bone tissue engineering and regenerative medicine. Their distinct physical features, such as high dielectric constant, ambipolar charge transfer, and ferroelectricity, make them ideal for bone regeneration. Perovskite-based scaffolds may replicate bone tissue's extracellular matrix and encourage cell behavior, hence aiding bone tissue regeneration. These materials have the potential to completely transform bone defect and injury therapy in regenerative medicine. However, issues like degradation, scalability, toxicity, device interaction, and cost must be solved before they can be widely used. To overcome these challenges, it is necessary to improve stability, scalability, and repeatability, reduce toxicity, achieve device compatibility, reduce manufacturing costs, and develop standardized testing and safety norms. To completely understand the biocompatibility and long-term effectiveness of perovskite materials in bone treatment, further studies and development are required. Despite these difficulties, perovskite materials offer promise in the treatment of bone abnormalities and fractures by acting as scaffolds for bone regeneration, medication delivery vehicles, and imaging agents. Overall, perovskite materials have the potential to improve bone regeneration and advance musculoskeletal disease therapies.

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