Abstract
Diabetes mellitus (DM) is a complex metabolic disorder whose rising
prevalence is terrible. A deeper knowledge of the pathophysiology of diabetes could
assist in discovering possible therapeutic targets for treating diabetes and its associated
problems. The common feature of diabetes, regardless of the specific pathology
involved, is hyperglycemia brought on by the death or dysfunction of β-cell. As insulin
deficiency gets worse over time, dysglycemia progresses in a continuum. This chapter
has provided a brief review of the pathophysiology of diabetes. Also, the roles of
genetics and environmental factors have been emphasized.
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