Probiotics Based Anticancer Immunity in Colorectal Cancer

Pp: 119-142 (24)

* (Excluding Mailing and Handling)

Abstract

Colorectal cancer (CRC) is the third most common cancer, originating in the colon and rectal region, leading to abnormal growth in the colon or rectal region. The gut microbiota plays a critical role in the maintenance of gut homeostasis, and dysbiosis in the gut microbiota has been associated with CRC pathogenesis. Probiotics can manipulate the gut microbiota, which can be effective in CRC treatment. Additionally, probiotics, through the modulation of host immune response, inhibition of tumor growth, reduction of microbial infection, inhibition of cancerogenic compounds, and regulation of apoptosis, can become a novel therapeutic option for the prevention and treatment of CRC. Therefore, this chapter mainly focuses on the mechanisms of probiotics-based anticancer immunity in CRC, so the existing knowledge could help in developing a safe and effective treatment for CRC.

Cite as