Abstract
Viral encephalitis is a major pathological situation. It can be caused either
by DNA or RNA viruses. Japanese encephalitis belongs to the member of flavivirus
and it is a mosquito-borne disease, causing viral disease. Japanese encephalitis can be
prevented by a vaccine. TLR3 and TLR4 signal pathways are activated due to JE
Japanese encephalitis infection. TLR3 and Retinoic acid-inducible I also participate in
mediating inflammation owing to Japanese encephalitis infection. In this kind of virus
infection first, the cells are infected, causing primary viremia, subsequently infecting
the CNS tissues as well. More than 60% of the world's population is living in JE
endemic places.
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