Neuroprotective Effect of Natural Products in Attenuation of Aging-associated Neurodegeneration

Abstract

Age-associated neurodegenerative disorders are a growing cause of mortality and morbidity in the elderly population globally. The patients suffering from neurodegenerative disorders pose medical, economic, and social issues. The agingassociated neurodegenerative disorders, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), have different clinical and neuropathological signatures, but they share a pattern of neurodegeneration in anatomical and functionally related regions. Natural products offer great potential in the prevention and therapy of neurodegenerative diseases. Plant-derived products protect neurons by targeting oxidative stress, mitochondrial dysfunction, neurotrophic factor deficit, and abnormal protein accumulation. The current chapter discusses the neuroprotective effect of natural products in the prevention of aging-associated neurodegenerative disorders.

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