Therapeutically Important Bioactive Compounds Derived from Fungal Origin

Pp: 223-235 (13)

* (Excluding Mailing and Handling)

Abstract

The rising of chronic ailments impinged on humans worldwide has paved the urgent need for newer therapeutic vital compounds that are biologically active and have the capacity to endeavour without exerting any adverse or cytotoxic effects. This necessitates extensive research to investigate unexplored natural sources for such promising sources. A diverse array of fungi species has garnered considerable attention over the past century due to the assortment of their opportunities to generate novel active ingredients with multifunction mechanisms towards recuperative applications. Some of the fungal bioactive compounds possess exclusive therapeutic potential and pharmaceutical importance. These efficacious bioactive compounds including Paclitaxel, Podophyllotoxin, Enniatins, Camptothecin, Ascophytatin with their properties like anti-bacterial, antiviral, anti-parasitic, anti-diabetic, anti-cancerous, immunomodulatory are discussed in this chapter.

Keywords: Endophytes, Topoisomerase, Karyokinetics, Anti malignant, Paclitaxel , Podophyllotoxin, Enniatins, Camptothecin, Ascophytatin.