Role of Nanomedicines in Ocular Targeting Drug Delivery Systems

Pp: 116-140 (25)

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Abstract

Ocular diseases have become a socioeconomic burden throughout the years. Blindness and visual impairment are the two most common ocular diseases worldwide. Not only do they affect the patient, but also the people surrounding them and the community that they are in. There are a lot of medications available for the treatment of ocular diseases, however, these have poor bioavailability because of the structure of the eyes and the barriers that they have. Nanotechnology has been providing significant contributions in the treatment of ocular diseases. Several studies and research are currently being focused on the development of nanomedicines that can achieve more than what the conventional routes of medications of ocular drugs can. Nanotechnology can also provide sustained and targeted delivery systems for ocular drugs. This chapter discusses the mechanisms that would enable nanoparticles to penetrate the ocular barriers and eventually increase the bioavailability of drugs intended to treat ocular diseases.

Keywords: Exosomes, Glaucoma, Nanomedicine, Ocular.

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