Alignment of Musculoskeletal System in Systemic Lupus Erythematosus

Abnormalities of joint alignment in systemic lupus erythematosus (SLE) are

characterized by subluxation or dislocation without erosion. Hand deformities (“lupus

hands”) in SLE patients include ulnar deviation, swan neck deformity, and thumb Z

deformity. However, abnormalities in alignment are widespread and can occur in the

wrists, shoulders, hips, knees, toes, and spine. Osteonecrosis and fracture can also

occur as alignment abnormalities. In addition, rheumatoid arthritis (RA) and other

complications such as scleroderma and inflammatory myositis may also occur, making

the alignment abnormalities complex. An understanding of alignment abnormalities in

SLE is helpful in diagnosing the condition of the disease and establishing a treatment

strategy. The purpose of this chapter is to provide an overview of alignment

abnormalities in SLE from various perspectives.

Keywords: Hand deformities, Joint alignment, Lupus hands, Systemic lupus erythematosus (SLE).

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DOI https://doi.org/10.2174/9789815050653122040004	Print ISSN 2468-6662
Publisher Name Bentham Science Publisher	Online ISSN 2468-6670

Systemic Lupus Erythematosus: A Systematic Approach to Arthritis of Rheumatic Diseases