Advancements of Transdermal Patches in Psychiatric Disorders

Pp: 331-341 (11)

Abstract

Non-adherence and non-compliance to the course of psychiatric medications affect the standard treatment plan of a patient. Inability to monitor the correct time and dosage also results in lesser efficiency of the drug and its action mechanism. Factors that may cause instability and non-compliance with the treatment plan are the possible side effects of drugs or the ease of use. With technological advancements in the field of drug delivery, transdermal patches, while Being non-invasive, ensure proper dosage and delivery of drugs through the skin, minimizing the first-pass metabolism. This review examines the existing literature, working mechanism, preclinical studies, and advancements in the application of transdermal patches in psychotropic drugs and deaddiction while evaluating various psychiatric disorders and comparing their efficacy and remission rate concerning standard oral treatment. It also addresses the challenges, drawbacks, and strategies required to increase its efficiency in clinical use.

Keywords: Affective Disorders, Transdermal Drug Delivery Systems, Schizophrenia, Substance Abuse Disorders, Sumatriptan Iontophoretic patch.

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