Transforming Growth Factor-Beta Family: Advances in Vascular Function and Signaling

Title:Transforming Growth Factor-Beta Family: Advances in Vascular Function and Signaling

Volume: 19 Issue: 12

Author(s): Sebastian Gatica, Claudio Cabello-Verrugio and Felipe Simon*

Affiliation:

• Laboratory of Integrative Physiopathology, Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas and Facultad de Medicina, Universidad Andres Bello, Santiago,Chile

Keywords: TGF, vascular, angiogenesis, hypertension, EndMT, fibrosis.

Abstract: This review includes a comprehensive, but succinct, summary on the essentials of TGF- β structure, family members, receptors, and intracellular mediators. Also provided is a select list of original publications that report novel roles and facets of TGF-β in vascular function and signaling in the contexts of health and disease.

Cite this article as:

Gatica Sebastian, Cabello-Verrugio Claudio and Simon Felipe *, Transforming Growth Factor-Beta Family: Advances in Vascular Function and Signaling, Current Protein & Peptide Science 2018; 19 (12) . https://dx.doi.org/10.2174/1389203719666171128114730