Abstract
The management of chondral defects has been a challenge for a long time because of the poor self-healing capacity of articular cartilage. Many approaches ranging from symptomatic treatment to structural cartilage regeneration are not that successful with very limited satisfactory results. Chondral defects caused by tumor, trauma, infection, congenital malformations are very common in clinical trials. It seriously affects the patient's physical function and quality of life. The appearance of cartilage tissue engineering has brought good news for cartilage defect repair. Through this review, we are aimed at reviewing the progress of the types and preparation techniques of scaffold materials in cartilage tissue engineering.
Keywords: Chondral defect, cartilage tissue engineering, scaffold, scaffold materials, scaffold fabrication technology, collagen.
Current Stem Cell Research & Therapy
Title:Research Progress of the Types and Preparation Techniques of Scaffold Materials in Cartilage Tissue Engineering
Volume: 13 Issue: 7
Author(s): Na Fu, Tengzhe Dong, Ai Meng, Zhaosong Meng, Bofeng Zhu and Yunfeng Lin*
Affiliation:
- State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041,China
Keywords: Chondral defect, cartilage tissue engineering, scaffold, scaffold materials, scaffold fabrication technology, collagen.
Abstract: The management of chondral defects has been a challenge for a long time because of the poor self-healing capacity of articular cartilage. Many approaches ranging from symptomatic treatment to structural cartilage regeneration are not that successful with very limited satisfactory results. Chondral defects caused by tumor, trauma, infection, congenital malformations are very common in clinical trials. It seriously affects the patient's physical function and quality of life. The appearance of cartilage tissue engineering has brought good news for cartilage defect repair. Through this review, we are aimed at reviewing the progress of the types and preparation techniques of scaffold materials in cartilage tissue engineering.
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Cite this article as:
Fu Na , Dong Tengzhe, Meng Ai , Meng Zhaosong , Zhu Bofeng and Lin Yunfeng *, Research Progress of the Types and Preparation Techniques of Scaffold Materials in Cartilage Tissue Engineering, Current Stem Cell Research & Therapy 2018; 13 (7) . https://dx.doi.org/10.2174/1574888X12666170718152611
DOI https://dx.doi.org/10.2174/1574888X12666170718152611 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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