Abstract
The present review summarizes the up to date developments on organobicyclo- bases namely 1,4-diazabicyclo[2.2.2]octane (DABCO), 1,8-diazabicyclo[5.4.0] undec-7-ene (DBU) and 1,5,7-triazabicyclo-[4,4,0]-dec-1-ene (TBD) catalyzed one-pot multi-component synthesis of biologically relevant heterocycles.
Keywords: Organo-bicyclo-base as catalyst, DABCO, DBU, TBD, multi-component reaction, bioactive heterocycles synthesis.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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