Atranorin – An Interesting Lichen Secondary Metabolite

Title:Atranorin – An Interesting Lichen Secondary Metabolite

Volume: 17 Issue: 17

Author(s): Elzbieta Studzinska-Sroka*, Agnieszka Galanty and Wieslawa Bylka

Affiliation:

• Department of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, Swiecickiego 4, 60-781 Poznan,Poland

Keywords: Atranorin, biological activity, biosynthesis, depside, lichen, secondary metabolites.

Abstract: Background: Atranorin, a compound with the depside structure, is one of the most common lichen secondary metabolites, characteristic for numerous lichen families but rarely found in some mosses and higher plants. Over the years various biological properties of atranorin were examined.

Objective: This review summarizes the studies on atranorin, focusing on a number of biological activities in different fields. The literature describes anti-inflammatory, analgesic, as well as wound healing, antibacterial, antifungal, cytotoxic, antioxidant, antiviral, and immunomodulatory activities of the depside. Furthermore, lack of toxicity of atranorin was confirmed in the animals' in vivo assays.

Conclusion: In conclusion, atranorin seems to be an interesting lichen substance, which needs to be investigated in more detail in order to allow further applications, e.g. in pharmacy, medicine or cosmetology.

Cite this article as:

Studzinska-Sroka Elzbieta*, Galanty Agnieszka and Bylka Wieslawa , Atranorin – An Interesting Lichen Secondary Metabolite, Mini-Reviews in Medicinal Chemistry 2017; 17 (17) . https://dx.doi.org/10.2174/1389557517666170425105727