Nanoscale Functional Biomaterials for Cancer Theranostics

Title:Nanoscale Functional Biomaterials for Cancer Theranostics

Volume: 25 Issue: 25

Author(s): Linying Liu, Xiaoshuang Li, Lei Chen*Xin Zhang*

Affiliation:

• Department of Obstetrics and Gynecology, Navy General Hospital of People Liberation Army, Beijing 100048,China

• State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190,China

Keywords: Nanomaterials, biomaterials, cancer, imaging, therapy, theranostics, liver tumor, gliomatosis cerebri.

Abstract: Nanomedicine is widely developed in recent years. In nanomedicine system, nanoscale and nanostructured functional materials are used to manipulate the human biology systems at the molecular level for cancer imaging and therapy. New nanostructure based functional materials consist of nanoscale liposomes, spheres, micelles, capsules, emulsion, suspension and phamacosomes. Several functional nanoparticles such as lipidbased and polymer-based materials are demonstrated to be drug delivery vehicles and imaging agents. These materials are biodegradable, biocompatible and have better biodistribution, lower side effect and lower toxicity. In addition, hybrids with these materials coating provide uniquely electrical, optical and magnetic properties. This review discusses the research on the applications of functional materials, especially nanoparticles as imaging contrast agents, cancer therapeutic agents and multi-functional agents and this review focused on the theranostic integration treatments on liver cancer and brain cancer.

Cite this article as:

Liu Linying , Li Xiaoshuang, Chen Lei *, Zhang Xin*, Nanoscale Functional Biomaterials for Cancer Theranostics, Current Medicinal Chemistry 2018; 25 (25) . https://dx.doi.org/10.2174/0929867324666170406111036