来自深海真菌的天然产物新型生物活性化合物的新来源？

Title:Natural Products from Deep-Sea-Derived Fungi ̶ A New Source of Novel Bioactive Compounds?

Volume: 25 Issue: 2

关键词: 深海真菌，极端微生物，天然产物，生物活性代谢物，药物发现，生物勘探。

摘要: Background: Over the last two decades, deep-sea-derived fungi are considered to be a new source of pharmacologically active secondary metabolites for drug discovery mainly based on the underlying assumption that the uniqueness of the deep sea will give rise to equally unprecedented natural products. Indeed, up to now over 200 new metabolites have been identified from deep-sea fungi, which is in support of the statement made above.

Results: This review summarizes the new and/or bioactive compounds reported from deepsea- derived fungi in the last six years (2010 – October 2016) and critically evaluates whether the data published so far really support the notion that these fungi are a promising source of new bioactive chemical entities.

Cite this article as:

Natural Products from Deep-Sea-Derived Fungi ̶ A New Source of Novel Bioactive Compounds?, Current Medicinal Chemistry 2018; 25 (2) . https://dx.doi.org/10.2174/0929867324666170314150121