Clinical Effectiveness and Cost-effectiveness of Target Therapies for Adult Patients with Locally Advanced or Metastatic Non-small Cell Lung Cancer: A Systematic Review

Title:Clinical Effectiveness and Cost-effectiveness of Target Therapies for Adult Patients with Locally Advanced or Metastatic Non-small Cell Lung Cancer: A Systematic Review

Volume: 18 Issue: 5

Author(s): Alessandra Bearz*, Massimiliano Berretta and Umberto Tirelli

Affiliation:

• Department of Medical Oncology, National Cancer Institute, Aviano (PN),Italy

Keywords: NSCLC, target agents, therapy, cost, chemotherapy, metastases, prognoses.

Abstract: Treatment for advanced non-small cell lung cancer has changed in the last two decades, with many new drugs, mostly target agents, included in the algorithm, improvement of progression free survival and overall survival, but also higher costs for health systems or health insurances.

Herein, we analyze the clinical effectiveness of target therapies for non-small cell lung cancer, according to their clinically meaningful outcome criteria and their cost impact.

Cite this article as:

Bearz Alessandra*, Berretta Massimiliano and Tirelli Umberto, Clinical Effectiveness and Cost-effectiveness of Target Therapies for Adult Patients with Locally Advanced or Metastatic Non-small Cell Lung Cancer: A Systematic Review, Current Cancer Drug Targets 2018; 18 (5) . https://dx.doi.org/10.2174/1568009617666170206112408