晚年抑郁症和阿尔茨海默病：潜在机制的潜在协同作用

Title:Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms

Volume: 25 Issue: 39

关键词: 衰老，阿尔茨海默病，抑郁症，痴呆症，BDNF晚年抑郁症

摘要: A number of biological and clinical characteristics typical of late life depression (LLD) have been suggested by recent research findings. The close association of LLD with cognitive impairment is now well documented and evidenced. However, it is still not clear whether it is depression that leads to cognitive decline, and in more severe cases, to dementia. The work presented in this review article suggests that depression and dementia frequently and strongly copresent, even if the causality remains largely opaque.

Cite this article as:

Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms, Current Medicinal Chemistry 2018; 25 (39) . https://dx.doi.org/10.2174/0929867323666160902152829